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Currently submitted to: JMIR mHealth and uHealth

Date Submitted: Feb 18, 2026
Open Peer Review Period: Feb 23, 2026 - Apr 20, 2026
(currently open for review)

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Wearable-Based Stress Detection for Real-World Data: Perspective on Challenges and Recommendations

  • Majid Hosseini; 
  • Raju Gottumukkala; 
  • Raviteja Bhupatiraju; 
  • Anthony Maida; 
  • Henry Chu

ABSTRACT

Background:

Machine learning methods succeed in stress detection under controlled laboratory conditions. However, transferring these models to real-world environments remains challenging. This performance gap is often considered as signal noise, overlooking fundamental issues in evaluation methodology and context-aware modeling.

Objective:

This work discusses the obstacles preventing the transition to real-world deployment and provides recommendations towards robust real-world stress detection methods.

Methods:

We synthesize current literature to map six critical challenges: high inter-subject physiological variability, motion/environmental artifacts, temporal signal misalignment, lack of contextual differentiation, biased ground truth labels, and inherent class imbalance in ambulatory data.

Results:

This perspective provides methodological recommendations for designing, evaluating, and reporting wearable stress detection studies, and strategies to avoid common experimental pitfalls, to ensure robust, trustworthy stress monitoring in real-world settings.

Conclusions:

: Reliable mHealth stress monitoring requires a shift from laboratory-based models to context-aware, subject-independent frameworks. By adopting the recommended evaluation and preprocessing standards, researchers can ensure that reported performance metrics reflect actual deployment reliability, improving the utility of wearable-based mental health interventions.


 Citation

Please cite as:

Hosseini M, Gottumukkala R, Bhupatiraju R, Maida A, Chu H

Wearable-Based Stress Detection for Real-World Data: Perspective on Challenges and Recommendations

JMIR Preprints. 18/02/2026:93741

DOI: 10.2196/preprints.93741

URL: https://preprints.jmir.org/preprint/93741

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