Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Currently submitted to: JMIR mHealth and uHealth

Date Submitted: Feb 18, 2026
Open Peer Review Period: Feb 23, 2026 - Apr 20, 2026
(closed for review but you can still tweet)

NOTE: This is an unreviewed Preprint

Warning: This is a unreviewed preprint (What is a preprint?). Readers are warned that the document has not been peer-reviewed by expert/patient reviewers or an academic editor, may contain misleading claims, and is likely to undergo changes before final publication, if accepted, or may have been rejected/withdrawn (a note "no longer under consideration" will appear above).

Peer review me: Readers with interest and expertise are encouraged to sign up as peer-reviewer, if the paper is within an open peer-review period (in this case, a "Peer Review Me" button to sign up as reviewer is displayed above). All preprints currently open for review are listed here. Outside of the formal open peer-review period we encourage you to tweet about the preprint.

Citation: Please cite this preprint only for review purposes or for grant applications and CVs (if you are the author).

Final version: If our system detects a final peer-reviewed "version of record" (VoR) published in any journal, a link to that VoR will appear below. Readers are then encourage to cite the VoR instead of this preprint.

Settings: If you are the author, you can login and change the preprint display settings, but the preprint URL/DOI is supposed to be stable and citable, so it should not be removed once posted.

Submit: To post your own preprint, simply submit to any JMIR journal, and choose the appropriate settings to expose your submitted version as preprint.

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Wearable-Based Stress Detection for Real-World Data: Perspective on Challenges and Recommendations

  • Majid Hosseini; 
  • Raju Gottumukkala; 
  • Raviteja Bhupatiraju; 
  • Anthony Maida; 
  • Henry Chu

ABSTRACT

Background:

Machine learning methods succeed in stress detection under controlled laboratory conditions. However, transferring these models to real-world environments remains challenging. This performance gap is often considered as signal noise, overlooking fundamental issues in evaluation methodology and context-aware modeling.

Objective:

This work discusses the obstacles preventing the transition to real-world deployment and provides recommendations towards robust real-world stress detection methods.

Methods:

We synthesize current literature to map six critical challenges: high inter-subject physiological variability, motion/environmental artifacts, temporal signal misalignment, lack of contextual differentiation, biased ground truth labels, and inherent class imbalance in ambulatory data.

Results:

This perspective provides methodological recommendations for designing, evaluating, and reporting wearable stress detection studies, and strategies to avoid common experimental pitfalls, to ensure robust, trustworthy stress monitoring in real-world settings.

Conclusions:

: Reliable mHealth stress monitoring requires a shift from laboratory-based models to context-aware, subject-independent frameworks. By adopting the recommended evaluation and preprocessing standards, researchers can ensure that reported performance metrics reflect actual deployment reliability, improving the utility of wearable-based mental health interventions.


 Citation

Please cite as:

Hosseini M, Gottumukkala R, Bhupatiraju R, Maida A, Chu H

Wearable-Based Stress Detection for Real-World Data: Perspective on Challenges and Recommendations

JMIR Preprints. 18/02/2026:93741

DOI: 10.2196/preprints.93741

URL: https://preprints.jmir.org/preprint/93741

Download PDF


Request queued. Please wait while the file is being generated. It may take some time.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.