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Accepted for/Published in: JMIR Infodemiology

Date Submitted: May 1, 2025
Open Peer Review Period: May 2, 2025 - Jun 27, 2025
Date Accepted: Jan 15, 2026
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Understanding Vaccine Hesitancy in Louisiana Through Social Media Listening and Community Feedback: Cross-Sectional Study

Sanchez AV, Ardoin J, Smith S, Sakhamuri S, Chu H

Understanding Vaccine Hesitancy in Louisiana Through Social Media Listening and Community Feedback: Cross-Sectional Study

JMIR Infodemiology 2026;6:e76827

DOI: 10.2196/76827

PMID: 42090582

PMCID: 13148589

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Understanding Vaccine Hesitancy in Louisiana: a study of social media listening and community feedback

  • Angie Viviana Sanchez; 
  • Julia Ardoin; 
  • Sadie Smith; 
  • Sahithya Sakhamuri; 
  • Henry Chu

ABSTRACT

INTRODUCTION: The rise of social media has significantly impacted public health programs, with platforms such as YouTube, Facebook, X (formerly Twitter), Instagram, and more recently, TikTok, being used to promote health information, raise awareness about disease outbreaks, and support disease prevention programs. However, the diverse and often unverified nature of the content on social media can make it challenging to discern accurate information, contributing to user uncertainty, which may contribute to low vaccination rates in some regions. This is especially true in Louisiana, as COVID-19 vaccination rates were among the lowest in the country in 2022. Therefore, understanding public sentiment on social media and developing targeted campaigns to counter unverified information is essential for advancing public health campaigns. METHODS: Social media listening was conducted using Meltwater, a media monitoring and social listening platform, supplemented by Google Alerts and Google News, to identify if vaccine-related stories or sentiments were attracting unusual attention. Additionally, a social media campaign aimed at educating Louisiana residents about disease manifestation, symptoms, vaccines available for disease prevention, and potential side effects was developed. Posts were published two to three times a week and boosted for seven days. RESULTS: From November 13, 2023, to June 11, 2024, social media listening identified at least 15 unique, noteworthy stories that signified sentiment spikes. These conversations were predominately related to vaccine hesitancy, with users expressing opposition to vaccines or reluctance to engaging with vaccine-related information. Sentiment spikes included themes related to mistrust of vaccines and concerns about their safety and efficacy. The social media campaign received 69,600 impressions, reached 43,429 users, received 652 reactions and likes, 62 shares, and 105 comments. Most of the audience was female, with higher engagement from older users on Facebook and younger users on Instagram. Finally, posts related to Hepatitis B, Rotavirus, and MMR vaccines received the most attention. DISCUSSION: Social media has become a key tool for digital health, helping to implement disease prevention programs and promoting advances in medicine. However, unverified information remains a major barrier to vaccination, despite the dissemination of information from reputable public health organizations and providers. To address this, information that is accessible, understandable, and culturally competent must be circulated to mitigate disinformation and improve attitudes toward vaccination. More research is needed to evaluate the effectiveness of social media campaigns in reducing vaccine hesitancy and improving willingness to adopt public health recommendations to increase vaccination rates.


 Citation

Please cite as:

Sanchez AV, Ardoin J, Smith S, Sakhamuri S, Chu H

Understanding Vaccine Hesitancy in Louisiana Through Social Media Listening and Community Feedback: Cross-Sectional Study

JMIR Infodemiology 2026;6:e76827

DOI: 10.2196/76827

PMID: 42090582

PMCID: 13148589

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