JMIR Publications

ABSTRACT

Recent advancements in cognitive neuroscience and digital technology have significantly accelerated the adoption of digital therapeutics for cognitive impairment. This review provides a comprehensive overview of the innovative applications of digital therapeutics in the assessment, intervention, management and monitoring of cognitive disorders, while highlighting key challenges that impede their widespread integration into clinical practice. Drawing on the definition of cognitive digital therapeutics and the multi-stakeholder collaboration required for its development and implementation, this study explores the role of digital technologies in cognitive health and explores challenges from multiple perspectives, including clinical practice, policy framework, user adoption, ethics and privacy, and data interoperability and security. Additionally, the study offers strategic recommendations to promote the sustainable development and scalable implementation of cognitive digital therapeutics, particularly as artificial intelligence (AI) technologies continue to advance, addressing both current applications and emerging challenges.