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Accepted for/Published in: JMIR Cancer

Date Submitted: Feb 14, 2025
Date Accepted: Dec 18, 2025

The final, peer-reviewed published version of this preprint can be found here:

Evaluating a Telehealth Coaching and Mobile-Based Digital Engagement Intervention for People With Cancer Using the Patient-Reported Outcomes Measurement Information System Global Health: Pilot Questionnaire Study

Lewis J, Wang S, Jue TR, Atkins T, Irwin SA, Sangar D, Mackenzie L, Murali-Ganesh R

Evaluating a Telehealth Coaching and Mobile-Based Digital Engagement Intervention for People With Cancer Using the Patient-Reported Outcomes Measurement Information System Global Health: Pilot Questionnaire Study

JMIR Cancer 2026;12:e72647

DOI: 10.2196/72647

PMID: 41920589

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Pilot study to evaluate a telehealth coaching and mobile based digital engagement intervention for people with cancer using PROMIS-10

  • Joanne Lewis; 
  • Shen Wang; 
  • Toni-Rose Jue; 
  • Tim Atkins; 
  • Scott A. Irwin; 
  • Davinder Sangar; 
  • Lynette Mackenzie; 
  • Raghav Murali-Ganesh

ABSTRACT

Background:

People with cancer often experience unmet needs during the acute and survivorship phases of treatment and rehabilitation, which can adversely impact their ability to perform everyday tasks and diminish their quality of life. Cancer Coach by Osara Health™️ is designed to address these holistic needs through telehealth coaching supported by a mobile application and digital participant engagement platform.

Objective:

This study evaluated the impact of Cancer Coach by Osara Health™️ on the mental and physical health of people with cancer.

Methods:

Participants were recruited via referrals from insurers and hospital clinics. Telephone self-assessed surveys administered by health coaches at the start and completion of the program measured global physical, mental and social health, using the Patient Reported Outcome Measurement Information System 10 - Question Short Form - Global Health (PROMIS-10). Pre- and post-scores were compared using Wilcoxon Signed Rank Tests to assess for significant difference between pre and post PROMIS-10 scores.

Results:

There were significant improvements in Global Physical Health, z=-4.966, p=<0.001, with more than a moderate effect size of r=0.37 and Global Mental Health, z=-4.533, p<0.01, with more than a moderate effect size of r=0.34 after the intervention. A significant number of participants improved their mental health scores from ‘good’ to ‘very good’ after the program.

Conclusions:

Participants demonstrated significant improvements in physical and mental health after participating in the Cancer Coach by Osara Health™️ intervention. Integrating telehealth coaching with asynchronous mobile app interventions may enhance emotional and mental health while also promoting physical well-being.


 Citation

Please cite as:

Lewis J, Wang S, Jue TR, Atkins T, Irwin SA, Sangar D, Mackenzie L, Murali-Ganesh R

Evaluating a Telehealth Coaching and Mobile-Based Digital Engagement Intervention for People With Cancer Using the Patient-Reported Outcomes Measurement Information System Global Health: Pilot Questionnaire Study

JMIR Cancer 2026;12:e72647

DOI: 10.2196/72647

PMID: 41920589

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