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Accepted for/Published in: JMIR Cancer

Date Submitted: Feb 14, 2025
Date Accepted: Dec 18, 2025

The final, peer-reviewed published version of this preprint can be found here:

Evaluating a Telehealth Coaching and Mobile-Based Digital Engagement Intervention for People With Cancer Using the Patient-Reported Outcomes Measurement Information System Global Health: Pilot Questionnaire Study

Lewis J, Wang S, Jue TR, Atkins T, Irwin SA, Nanda P, Mackenzie L, Murali-Ganesh R

Evaluating a Telehealth Coaching and Mobile-Based Digital Engagement Intervention for People With Cancer Using the Patient-Reported Outcomes Measurement Information System Global Health: Pilot Questionnaire Study

JMIR Cancer 2026;12:e72647

DOI: 10.2196/72647

PMID: 41920589

Pilot study to evaluate a telehealth coaching and mobile based digital engagement intervention for people with cancer using PROMIS Global Health

  • Joanne Lewis; 
  • Shen Wang; 
  • Toni-Rose Jue; 
  • Tim Atkins; 
  • Scott A. Irwin; 
  • Puneet Nanda; 
  • Lynette Mackenzie; 
  • Raghav Murali-Ganesh

ABSTRACT

Background:

People with cancer often experience unmet needs during treatment and survivorship, which can impact their ability to carry out daily tasks, reduce their quality of life, and limit their participation in work and social activities. Cancer Coach by CancerAid™ is a digital health intervention designed to address these needs through a combination of synchronous telehealth coaching and an asynchronous mobile app that supports behaviour change and emotional well-being.

Objective:

This study aimed to evaluate the impact of Cancer Coach by CancerAid™ on the mental and physical health of people with cancer using patient-reported outcomes.

Methods:

Participants were referred to the program via insurers and hospital clinics. Health coaches administered the Patient-Reported Outcome Measurement Information System 10-Question Short Form – Global Health (PROMIS-10) via telephone at both the beginning and end of the intervention. This tool measures Global Physical Health (GPH) and Global Mental Health (GMH). Pre- and post-intervention scores were analysed using Wilcoxon Signed Rank Tests. Independent t-tests assessed whether changes in GPH and GMH scores were associated with the use of health coaching alone or in combination with the mobile app.

Results:

Statistically significant improvements were observed in both Global Physical Health (GPH) (z = -4.97, P < .001, r = 0.37) and Global Mental Health (GMH) (z = -4.53, P < .01, r = 0.34), indicating moderate effect sizes in the 89 participants. The average T-score point changes of 4.43 for GPH and 4.58 for GMH represent a minimal important change (MIC) for participants. The improvement in group GMH T-score is reflected in the move from “good” to “very good” mental health status. Participants who engaged with both health coaching and the mobile app showed greater improvements in physical health, whereas those who received health coaching alone demonstrated higher gains in mental health. This suggests that the mode of support may influence specific health outcomes.

Conclusions:

Use of the PROMIS-10 showed participants had significant improvements in physical and mental health after participating in the Cancer Coach by CancerAid™️ intervention. The integration of telehealth coaching with app-based support may enhance overall well-being and address holistic needs during cancer treatment and survivorship.


 Citation

Please cite as:

Lewis J, Wang S, Jue TR, Atkins T, Irwin SA, Nanda P, Mackenzie L, Murali-Ganesh R

Evaluating a Telehealth Coaching and Mobile-Based Digital Engagement Intervention for People With Cancer Using the Patient-Reported Outcomes Measurement Information System Global Health: Pilot Questionnaire Study

JMIR Cancer 2026;12:e72647

DOI: 10.2196/72647

PMID: 41920589

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