Previously submitted to: JMIRx Med (no longer under consideration since Jun 18, 2025)
Date Submitted: Jan 25, 2025
Open Peer Review Period: Jan 28, 2025 - Mar 25, 2025
(closed for review but you can still tweet)
NOTE: This is an unreviewed Preprint
Warning: This is a unreviewed preprint (What is a preprint?). Readers are warned that the document has not been peer-reviewed by expert/patient reviewers or an academic editor, may contain misleading claims, and is likely to undergo changes before final publication, if accepted, or may have been rejected/withdrawn (a note "no longer under consideration" will appear above).
Peer review me: Readers with interest and expertise are encouraged to sign up as peer-reviewer, if the paper is within an open peer-review period (in this case, a "Peer Review Me" button to sign up as reviewer is displayed above). All preprints currently open for review are listed here. Outside of the formal open peer-review period we encourage you to tweet about the preprint.
Citation: Please cite this preprint only for review purposes or for grant applications and CVs (if you are the author).
Final version: If our system detects a final peer-reviewed "version of record" (VoR) published in any journal, a link to that VoR will appear below. Readers are then encourage to cite the VoR instead of this preprint.
Settings: If you are the author, you can login and change the preprint display settings, but the preprint URL/DOI is supposed to be stable and citable, so it should not be removed once posted.
Submit: To post your own preprint, simply submit to any JMIR journal, and choose the appropriate settings to expose your submitted version as preprint.
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
The Rise of Antibiotic Resistance and Its Global Impact
ABSTRACT
Antimicrobial resistance (AMR) presents a significant challenge to global public health, as overuse and misuse of antibiotics have led to the emergence of resistant bacteria, making infections more difficult and expensive to treat. This article explores the rise of antibiotic resistance, its impact on treatment regimens, and case studies highlighting the emergence of resistant organisms like Klebsiella pneumoniae, Mycobacterium tuberculosis, and Enterococcus faecium. It examines the causes of AMR, including overprescription in healthcare, agricultural use of antibiotics, and inadequate infection control measures, alongside the economic and ecological implications. Recent advancements in research, such as new antibiotic development, bacteriophage therapy, and antimicrobial peptides, offer potential solutions, but the need for global collaboration and improved stewardship programs is crucial. The article stresses the importance of continued research, surveillance, and the development of alternative therapies to combat AMR and mitigate its widespread impact on both public health and the economy.
Citation
Request queued. Please wait while the file is being generated. It may take some time.
Copyright
© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.