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Accepted for/Published in: JMIR Research Protocols

Date Submitted: Aug 9, 2022
Date Accepted: Mar 12, 2023
Date Submitted to PubMed: May 16, 2023

The final, peer-reviewed published version of this preprint can be found here:

Airway Sequelae After Mechanical Ventilation for COVID-19: Protocol for a Scoping Review

Candelo E, Arias-Valderrama O, Triviño-Arias J, Quiroz F, Isaza-Pierotti DF, Victoria W, Tintinago LF

Airway Sequelae After Mechanical Ventilation for COVID-19: Protocol for a Scoping Review

JMIR Res Protoc 2023;12:e41811

DOI: 10.2196/41811

PMID: 37191952

PMCID: 10719820

Airway sequelae after mechanical ventilation for COVID-19: a scoping review protocol

  • Estephania Candelo; 
  • Oriana Arias-Valderrama; 
  • Jacobo Triviño-Arias; 
  • Felipe Quiroz; 
  • Daniel Francisco Isaza-Pierotti; 
  • William Victoria; 
  • Luis F Tintinago

ABSTRACT

Background:

The epidemiology, morbidity, and burden of the disease related to airway sequelae associated with invasive mechanical ventilation (IMV) in the context of the COVID-19 pandemic remain unclear. This scoping review aims to provide a summary of the current knowledge regarding these conditions. This knowledge will help guide research endeavors and decision-making in clinical practice.

Objective:

This scoping review aims to provide a summary of the current knowledge regarding these conditions. This knowledge will help guide research endeavors and decision-making in clinical practice.

Methods:

This scoping review will include participants of all genders and no particular age group who developed post-COVID airway related complication will be excluded. No exclusion criteria will be applied from country, language or document type. The information source will include analytical observational, observational studies. Unpublished data will not be completely covered as grey literature will be covered. A total of 2 independent reviewers will participate in the process of screening, selection, and data extraction, and the whole process will be performed blindly. Conflict between reviewers will be solve through discussion and additional reviewer. Results will be reported by using descriptive statistics and information will be displayed on RedCap.

Results:

The literature search was conducted in May 2022 in in the following databases; PubMed, EMBASE, SCOPUS, EBSCO, Google Scholar, Cochrane Library, and Grey literature to identify observational studies; a total of 738 results were retrieved. The scoping review will be finished by early-2023

Conclusions:

This scoping review will describe current knowledge on the most frequently encountered laryngeal and/or tracheal sequelae in patients exposed to mechanical ventilation due to SARS-CoV-2 infection. This scoping review will find the incidence of airway sequelae post-COVID19 and the most common sequelae such as; airway granuloma, vocal fold paralysis, and airway stenoses. Future studies should evaluate the incidence of these disorders. Clinical Trial: OSF registrated


 Citation

Please cite as:

Candelo E, Arias-Valderrama O, Triviño-Arias J, Quiroz F, Isaza-Pierotti DF, Victoria W, Tintinago LF

Airway Sequelae After Mechanical Ventilation for COVID-19: Protocol for a Scoping Review

JMIR Res Protoc 2023;12:e41811

DOI: 10.2196/41811

PMID: 37191952

PMCID: 10719820

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