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Accepted for/Published in: JMIR AI

Date Submitted: Apr 30, 2026
Date Accepted: Jul 28, 2026

The final, peer-reviewed published version of this preprint can be found here:

From Personalization to Therapeutic Continuity: Framework for Memory in AI-Powered Mental Health Systems

Jewell C, McAlister K, Deliberto T, Wallis T, Winns G, Huberty J

From Personalization to Therapeutic Continuity: Framework for Memory in AI-Powered Mental Health Systems

JMIR AI 2026;5:e99950

DOI: 10.2196/99950

From Personalization to Therapeutic Continuity: A Framework for Memory in AI-Powered Mental Health Systems

  • Courtney Jewell; 
  • Kelsey McAlister; 
  • Tara Deliberto; 
  • Tanner Wallis; 
  • Grant Winns; 
  • Jennifer Huberty

ABSTRACT

Artificial intelligence (AI) powered mental health tools are increasingly deployed to support users across multiple sessions, yet the field lacks a principled framework for how memory in these systems should be structured and applied. In most current implementations, memory functions primarily as a personalization mechanism, optimizing for conversational continuity and user engagement without distinguishing between types of information that serve fundamentally different clinical functions. We propose a framework organizing memory in AI-powered mental health systems into four functionally distinct types. Episodic memory captures discrete, time-bound experiences tied to specific events and context. Pattern memory, adapted from the concept of procedural memory in cognitive psychology, tracks recurring patterns in cognition, emotion, and behavior across sessions. Semantic memory captures stable, personally relevant background context about the user. State-responsive memory represents the user's current emotional and psychological condition in real time, taking priority over the other three types when acute distress or risk is signaled. Each type corresponds to a distinct clinical function, and together they are designed to support the kind of cumulative, longitudinal understanding that effective mental health care requires. We term this framework therapeutically informed memory, drawing on established memory systems research and applied to the clinical requirements of AI-powered mental health support. We describe the design requirements and clinical rationale for each memory type, discuss how the types interact and how priority should be assigned across them, and use Yuna, an AI-powered digital mental health intervention developed with clinical input, as an illustrative example of how this framework can be applied in practice. We conclude with design implications for the field and identify open questions regarding memory quality metrics, outcome validation, and the ethical dimensions of persistent memory as priorities for future research.


 Citation

Please cite as:

Jewell C, McAlister K, Deliberto T, Wallis T, Winns G, Huberty J

From Personalization to Therapeutic Continuity: Framework for Memory in AI-Powered Mental Health Systems

JMIR AI 2026;5:e99950

DOI: 10.2196/99950

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