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Mobile health application to screen for central sleep apnea in patients with stable heart failure
Roderick Willem Treskes;
Arie C Maan;
Harriette Florence Verwey;
Robert Schot;
Saskia Lambertha Maria Anna Beeres;
Laurens F Tops;
Enno Tjeerd Van Der Velde;
Martin Jan Schalij;
Annelies Margaretha Slats
ABSTRACT
Background:
Polysomnography (PSG) is the gold standard for detection of central sleep apnea (CSA) in stable heart failure (HF) patients. PSG is however costly, time consuming and a burden to the patient and therefore unsuitable as screening method. An E-Health application to measure overnight oximetry may be an acceptable screening alternative.
Objective:
The purpose of this study is therefore to assess if overnight pulse oximetry using a smartphone compatible oximeter can be used to detect CSA in a stable HF population.
Methods:
A total of 26 patients with stable HF underwent one night of both a polygraph (PG) and overnight saturation by a smartphone compatible oximeter. Primary endpoint was the agreement between oxygen desaturation index (ODI) above or below 15 of the smartphone compatible oximeter and the diagnosis of the PG.
Results:
Median age was 66.4 (62-71) years and 92% was male. Body mass index was 27.1 (24.4-30.8) kg•m-2. Seven patients had CSA and 6 patients had obstructive sleep apnea. Of the 7 (.32) patients with CSA that were included in the analysis, 3 (.13) had an ODI≥15. The other 4 (.18) had an ODI<15. Of all patients without CSA, 8 (.36) had an ODI<15. A McNemar’s test yielded a P-Value of .549.
Conclusions:
Oxygen desaturation, when measured by this E-Health application, is a weak predictor of CSA in stable HF patients. Clinical Trial: Not applicable
Citation
Please cite as:
Treskes RW, Maan AC, Verwey HF, Schot R, Beeres SLMA, Tops LF, Van Der Velde ET, Schalij MJ, Slats AM
Mobile Health for Central Sleep Apnea Screening Among Patients With Stable Heart Failure: Single-Cohort, Open, Prospective Trial
