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Accepted for/Published in: JMIR Research Protocols

Date Submitted: Jan 14, 2018
Open Peer Review Period: Jan 14, 2018 - Mar 21, 2018
Date Accepted: Mar 22, 2018
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Safer Prescribing and Care for the Elderly (SPACE): Protocol of a Cluster Randomized Controlled Trial in Primary Care

Wallis KA, Elley CR, Lee A, Moyes S, Kerse N

Safer Prescribing and Care for the Elderly (SPACE): Protocol of a Cluster Randomized Controlled Trial in Primary Care

JMIR Res Protoc 2018;7(4):e109

DOI: 10.2196/resprot.9839

PMID: 29699966

PMCID: 5945992

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Safer Prescribing and Care for the Elderly (SPACE): Protocol of a Cluster Randomized Controlled Trial in Primary Care

  • Katharine Ann Wallis; 
  • Carolyn Raina Elley; 
  • Arier Lee; 
  • Simon Moyes; 
  • Ngaire Kerse

Background:

High-risk prescribing, adverse drug events, and avoidable adverse drug event hospitalizations are common. The single greatest risk factor for high-risk prescribing and adverse drug events is the number of medications a person is taking. More people are living longer and taking more medications for multiple long-term conditions. Most on-going prescribing occurs in primary care. The most effective, cost-effective, and practical approach to safer prescribing in primary care is not yet known.

Objective:

To test the effect of the Safer Prescribing And Care for the Elderly (SPACE) intervention on high-risk prescribing of nonsteroidal anti-inflammatory and antiplatelet medicines, and related adverse drug event hospitalizations.

Methods:

This is a protocol of a cluster randomized controlled trial. The clusters will be primary care practices. Data collection and analysis will be at the level of patient.

Results:

Recruitment started in 2018. Six-month data collection will be in 2018.

Conclusions:

This study addresses an important translational gap, testing an intervention designed to prompt medicines review and support safer prescribing in routine primary care practice.

ClinicalTrial:

Australian New Zealand Clinical Trials Registry: ACTRN12618000034235 http://www.ANZCTR.org.au/ACTRN12618000034235.aspx (Archived with Webcite at http://www.webcitation.org/6yj9RImDf)


 Citation

Please cite as:

Wallis KA, Elley CR, Lee A, Moyes S, Kerse N

Safer Prescribing and Care for the Elderly (SPACE): Protocol of a Cluster Randomized Controlled Trial in Primary Care

JMIR Res Protoc 2018;7(4):e109

DOI: 10.2196/resprot.9839

PMID: 29699966

PMCID: 5945992

Per the author's request the PDF is not available.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.