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Accepted for/Published in: JMIR Medical Informatics

Date Submitted: Mar 30, 2026
Date Accepted: Oct 7, 2026

The final, peer-reviewed published version of this preprint can be found here:

Automated Detection of Abnormal Pediatric Electroencephalograms Using Machine Learning: Retrospective Study

Poggi L, Flaschel N, Becker SS, Nensa F, Kohnke J, Greve S, Paul L, Dohna-Schwake C, Felderhoff-Müser U, Della Marina A, Stein CJ, Hosch R, Bruns N

Automated Detection of Abnormal Pediatric Electroencephalograms Using Machine Learning: Retrospective Study

JMIR Med Inform 2026;14:e96601

DOI: 10.2196/96601

Automated Detection of Abnormal Pediatric Electroencephalograms Using Machine Learning: A Retrospective Study

  • Leonardo Poggi; 
  • Nils Flaschel; 
  • Sven Steffen Becker; 
  • Felix Nensa; 
  • Judith Kohnke; 
  • Sandra Greve; 
  • Luisa Paul; 
  • Christian Dohna-Schwake; 
  • Ursula Felderhoff-Müser; 
  • Adela Della Marina; 
  • Christopher Johannes Stein; 
  • René Hosch; 
  • Nora Bruns

ABSTRACT

Background:

Electroencephalography (EEG) is widely used in medicine as a technique for the assessment of several brain-related pathologies. However, the interpretation of EEG signals is a strenuous task that requires the expertise of trained neurologists and has relatively low inter-rater agreement.

Objective:

To address this problem by using artificial intelligence methods to automate EEG interpretation and compare the performance of different modeling approaches.

Methods:

A gradient boosting–based model, inspired by the work of Albaqami et al., was implemented and compared to deep learning–based models using convolutional neural networks to classify images generated from raw EEG signals. The models were trained and tested on pediatric EEGs acquired at the University Hospital in Essen.

Results:

The deep learning model demonstrated superior sensitivity (78.3%) and F1-score (80.0%) compared to the gradient boosting model (sensitivity: 68.1%, F1-score: 76.4%), indicating improved detection of abnormal EEGs. However, the gradient boosting approach achieved higher specificity (93.7% vs. 89.6%), suggesting a stronger ability to recognize normal EEGs. Overall, both methods yielded promising results, with classification accuracies reaching up to 85%.

Conclusions:

Both approaches show potential for automated EEG interpretation. Future improvements, including larger and more diverse datasets, refined deep learning architectures, and integration of explainable AI techniques, could further enhance performance.


 Citation

Please cite as:

Poggi L, Flaschel N, Becker SS, Nensa F, Kohnke J, Greve S, Paul L, Dohna-Schwake C, Felderhoff-Müser U, Della Marina A, Stein CJ, Hosch R, Bruns N

Automated Detection of Abnormal Pediatric Electroencephalograms Using Machine Learning: Retrospective Study

JMIR Med Inform 2026;14:e96601

DOI: 10.2196/96601

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