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Age- and sex- specific distribution of the TyG index in a large Chinese population
Hanze Du;
Shuaihua Song;
Xiao Zhai;
Junchi Liu;
Yue Jiang;
Yaoda Hu;
Huijing He;
Daowei Li;
Huijuan Zhu;
Shi Chen;
Guangliang Shan;
Hui Pan
ABSTRACT
Background:
The TyG index has demonstrated promising predictive capability in clinical studies, but its reference range has not been uniformly defined. Defining population-specific reference ranges for the TyG index is important to enhance the accuracy of disease diagnosis and treatment.
Objective:
The TyG index has demonstrated promising predictive capability in clinical studies, but its reference range has not been uniformly defined. Defining population-specific reference ranges for the TyG index is important to enhance the accuracy of disease diagnosis and treatment.
Methods:
A total of 4621 participants aged 20-80 from the China National Health Survey were included in this study. TyG index was calculated from fasting blood glucose and triglycerides. The age- and sex-specific reference values of TyG index were obtained using the percentiles method.
Results:
Males had higher BMI (23.32 ± 2.63 vs. 22.72 ± 2.60 kg/m2), TG (133.78 ± 78.07 vs. 111.58 ± 61.18 mg/dl), GLU (97.05 ± 11.95 vs. 94.34 ± 10.46 mg/dl), and TyG index (8.63 ± 0.54 vs. 8.45 ± 0.50) than females. The TyG index of males reached peak value at approximately the age of 40 years. The lower limit reference range for females exceeded that of males around age 50. After the age of 60, the upper limit of the reference value in females was higher than males.
Conclusions:
This study established age- and sex-specific reference values for TyG index for Chinese people aged 20-80 years. The results of this study contribute to a more precise assessment of glucolipid metabolism. Clinical Trial: Not applicable.
Citation
Please cite as:
Du H, Song S, Zhai X, Liu J, Jiang Y, Hu Y, He H, Li D, Zhu H, Chen S, Shan G, Pan H
Age- and Sex-Specific Distribution of the Triglyceride-Glucose Index in a Large Chinese Population: Cross-Sectional Study