Previously submitted to: Interactive Journal of Medical Research (no longer under consideration since Mar 02, 2026)
Date Submitted: Mar 2, 2026
Open Peer Review Period: Mar 2, 2026 - Mar 2, 2026
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Research and Collaboration on Wolbachia and Aedes aegypti: A Scientometric Analysis
ABSTRACT
Background:
Aedes aegypti is one of the vectors of dengue, Zika and Chikungunya. The use of Wolbachia as a biological control agent in Aedes aegypti has gained significant global attention following the successful establishment of field-released mosquitoes in Australia, Malaysia, Brazil, Indonesia and Singapore.
Objective:
This study presents a scientometric analysis of research on Wolbachia and Aedes aegypti, and quantifying key findings.
Methods:
Data were extracted from the Scopus database, including English-language articles, reviews, books and book chapters published between 2000 and 2025. Relative growth rate was generated to examine the change in the number of publications per year. Analysis tools such as Vosviewer, CiteSpace, and the R-based Biblioshiny were employed to examine prolific authors, publication and citation trends, collaboration networks, and thematic evolution. Bradford’s Law analysis was used to examine the core journals that contribute most to the dissemination of research in this area.
Results:
The findings reveal that Ary Hoffmann is the most prolific author, while Australia leads as the most productive country. Research activity across 13 thematic clusters has intensified over time, with emerging focus areas including “prevalence distribution”, “Wolbachia strain” and “Wolbachia-mediated sterility”. The low percentage of error (0.6%) suggests that the data fits the Bradford’s distribution pattern, with PLoS Neglected Tropical Diseases (79) and Parasites and Vectors (39) as top journal.
Conclusions:
Overall, the study provides a comprehensive overview of the intellectual landscape, collaboration patterns, and emerging trends in Wolbachia-Aedes aegypti research, underscoring global collaboration and emerging trends that have the potential to advance innovative and sustainable approaches to vector control for dengue and other arboviral diseases.
Citation
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