JMIR Publications

ABSTRACT

Background:

In older adults with chronic constipation, symptoms of defecation difficulty often persist despite improvements in bowel movement frequency. However, constipation-related symptoms have rarely been examined as independent outcomes.

Objective:

To explore factors associated with constipation-related symptoms, <3 spontaneous bowel movements per week, straining during bowel movements, sensation of incomplete evacuation, and sensation of anorectal obstruction or blockage.

Methods:

A cross-sectional web-based survey was conducted for the collection of patient-reported data. Constipation-related symptoms were defined according to the Rome IV criteria. Each symptom was treated as a binary variable in the analyses. Multivariable logistic regression analyses were used to examine associations between stool characteristics and medication, treatment processes, and lifestyle-related factors. Stool characteristics were classified using the Bristol Stool Form Scale, with hard stools defined as type 1 and 2.

Results:

We enrolled 546 participants and investigated the following constipation symptoms: <3 spontaneous bowel movements per week (41.4%), straining (60.4%), sensation of incomplete evacuation (63.0%), and sensation of anorectal obstruction or blockage (44.3%). Multivariable logistic regression analyses for these outcome variables showed that hard stool was consistently and independently associated with all constipation-related symptoms (odds ratio [OR] 1.86–4.66). Symptom-specific associations that remained significant after false discovery rate adjustment included lower physical activity with < 3 spontaneous bowel movements per week (OR 0.86, 95% CI 0.77–0.96), stimulant laxative use with sensation of incomplete evacuation (OR 2.01, 95% CI 1.22–3.31), and lower adherence to the prescribed dosage with sensation of anorectal obstruction or blockage (OR 0.87, 95% CI 0.78–0.97). In contrast, experience of adverse effects was associated with a higher probability of <3 spontaneous bowel movements per week and sensation of anorectal obstruction or blockage.

Conclusions:

In older adults with chronic constipation, different constipation-related symptoms showed distinct patterns of association, while hard stool consistency emerged as a common factor across symptoms. These exploratory findings may support symptom-oriented assessment and help inform individualized management approaches using electronically collected patient-reported outcomes.