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Currently submitted to: Journal of Medical Internet Research

Date Submitted: Feb 4, 2026
Open Peer Review Period: Feb 5, 2026 - Apr 2, 2026
(currently open for review)

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Impact of intelligent robot-aided task-oriented physiotherapy on patients’ musculoskeletal system compared with constant-support robot-aided treatment and physiotherapist-guided therapy – medical experiment

  • Piotr Falkowski; 
  • Kajetan Jeznach; 
  • Jan Oleksiuk; 
  • Tomasz Osiak; 
  • Maciej Pikuliński; 
  • Andrzej Zakręcki; 
  • Krzysztof Zawalski; 
  • Piotr Kołodziejski; 
  • Daniel Śliż

ABSTRACT

Background:

Task-oriented rehabilitation supported by exoskeletons has the potential to increase therapy intensity, personalization, and accessibility. However, to achieve fully automatic treatment, robotized systems need to analyze therapy in a more complex way than only based on reference trajectories following.

Objective:

This study investigates the effects of an intelligent, context-aware control algorithm for an upper-limb rehabilitation exoskeleton on patients’ musculoskeletal engagement, compared with constant-admittance robot-assisted therapy and conventional physiotherapist-guided treatment.

Methods:

A single-session experimental study was conducted with 34 adult participants performing six activities of daily living under three therapy modes: robot-assisted therapy with constant admittance, robot-assisted therapy with an intelligent assist-as-needed algorithm, and physiotherapist-guided therapy. Muscle activity was assessed using surface electromyography of eight upper-limb muscle groups, while joint kinematics were recorded using inertial measurement units. Metrics included EMG power, muscle activation time, joint range of motion, and burst duration similarity indices. Statistical comparisons were performed using the T-test and the Mann-Whitney U-test depending on data normality.

Results:

Results indicate that the intelligent control strategy engages the musculoskeletal system at least as effectively as constant-admittance control across all exercises. At the same time, more motion control is given to the patient, which is preferable for neuroplasticity training. Compared with physiotherapist-guided therapy, robot-assisted treatment with intelligent control elicited significantly higher and more consistent muscular engagement. Intelligent assistance also modified joint-level motion patterns by reducing compensatory movements, particularly in shoulder–elbow coupling, while maintaining functional task execution. Muscle activation timing patterns during intelligent robot-assisted therapy were more consistent with robotic control than with manual therapy, reflecting altered movement strategies.

Conclusions:

These findings demonstrate that context-aware, intelligent control in rehabilitation exoskeletons can promote active patient participation, reduce compensatory behaviors, and maintain physiologically meaningful muscle engagement. The proposed approach exceeds the results of recent similar studies, being a promising step toward effective, minimally supervised, task-oriented rehabilitation. Clinical Trial: The experiments were carried out under the KB/132/2024 approval of the Bioethical Committee of the Medical University of Warsaw (https://komisja-bioetyczna.wum.edu.pl/). Written informed consent was obtained from all of the subjects involved in this study.


 Citation

Please cite as:

Falkowski P, Jeznach K, Oleksiuk J, Osiak T, Pikuliński M, Zakręcki A, Zawalski K, Kołodziejski P, Śliż D

Impact of intelligent robot-aided task-oriented physiotherapy on patients’ musculoskeletal system compared with constant-support robot-aided treatment and physiotherapist-guided therapy – medical experiment

JMIR Preprints. 04/02/2026:92898

DOI: 10.2196/preprints.92898

URL: https://preprints.jmir.org/preprint/92898

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