Accepted for/Published in: JMIR Formative Research
Date Submitted: Jan 25, 2026
Date Accepted: Apr 24, 2026
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
Adaptation of a smartphone-based mobile health program to support person-centered treatment of tuberculosis in Kilimanjaro, Tanzania: A pre-implementation qualitative needs assessment
ABSTRACT
Background:
Despite increasing smartphone penetration globally, personalized mobile health (mHealth) care interventions remain largely untapped for support of people with tuberculosis (TB). An evidence-based multi-feature smartphone platform for HIV care tailored and widely implemented in the US may enhance treatment quality and completion in the Kilimanjaro context.
Objective:
We aimed to evaluate contextual determinants of mHealth implementation in the Kilimanjaro region to ensure feasibility, acceptability, and effective adaptation of the platform for TB care within Kilimanjaro.
Methods:
We conducted semi-structured in-depth interviews at Kilimanjaro Christian Medical Centre (KCMC) and Kibong’oto Infectious Diseases Hospital (KIDH) with people with TB (PWTB) (aged 18+ with drug-susceptible/-resistant TB, with/without HIV, and > 1 month on treatment) and providers/staff (e.g. clinicians, community health workers, laboratory staff). Interview guides were designed using Bury’s Framework for Chronic Illness and the Consolidated Framework for Implementation Research (CFIR), along with an overview of an existing smartphone-based program called PositiveLinks.
Results:
We conducted 14 interviews with PWTB and 11 provider/staff interviews. Several unmet TB treatment needs emerged along with suggestions for platform adaptation and implementation strategies. Findings suggest high personal smartphone access among providers/staff (100%), less so for PWTB interviewed (36%). High provider digital literacy/capability and usage was noted, with smartphone apps routinely used for TB care delivery independent of electronic health systems. PWTB primarily used mobile phones for communication (calls) with clinic providers and staff for care coordination (e.g. reminders). Internet access and stability remain a barrier in rural clinics, along with personal cost of data bundles for both stakeholder groups. Key assets identified within the inner setting of KCMC and KIDH include existing provider/staff commitment to treatment support outside of clinic visits, and a robust infrastructure of community outreach for support of adherence and retention for PWTB.
Conclusions:
Real-world considerations for the context suggest implementation of provider-facing smartphone interventions would be highly feasible and acceptable with appropriate consideration of personal cost associated with usage among stakeholders. Patient-facing or bi-directional tools would require modifications to existing mHealth implementation strategies, including more comprehensive assessment of digital literacy and related training, as well as provision of subsidized devices and data bundles.
Citation
Request queued. Please wait while the file is being generated. It may take some time.
Copyright
© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.