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Currently submitted to: JMIR Formative Research

Date Submitted: Jan 15, 2026

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Holistic and economic benefits of comprehensive obesity care: 6 month real-world outcomes from a digital UK Tier-3 service

  • Dagmara Wozniak; 
  • Felix Schirmann; 
  • Waseem Majeed; 
  • Lucy Jones

ABSTRACT

Background:

Obesity is a complex chronic disease that disproportionately affects people living in socioeconomic deprivation. Although randomised trials demonstrate the efficacy of pharmacological and digital interventions, evidence on their real-world effectiveness regarding behavioral mechanisms, holistic health outcomes, and economic impact in routine care settings remains limited.

Objective:

This real-world evidence study evaluated 738 adults enrolled in the Oviva UK Tier-3 digital service.

Methods:

Outcomes at baseline, 3 and 6 months included body weight, lifestyle behaviors, psychosocial health, sickness-related absence from work, healthcare use, and engagement with Oviva App. Correlational and multivariable models examined predictors of weight change.

Results:

Participants achieved clinically meaningful weight loss (-2.7% at 3 months; -8.6% at 6 months). Improvements were also observed across general and mental health, physical functioning, quality of life, dietary habits, alcohol intake, sickness-related absence, and healthcare utilisation (all P<.05). Sick days decreased by 50% after six months of Oviva care. Greater self-monitoring and Oviva App engagement predicted larger weight losses.

Conclusions:

The digital Tier-3 service produced substantial weight loss and broad behavioral, psychosocial and economic benefits. Engagement with Oviva App was a key driver of success, supporting the role of scalable Tier-3 services in expanding access and enhancing NHS obesity care.


 Citation

Please cite as:

Wozniak D, Schirmann F, Majeed W, Jones L

Holistic and economic benefits of comprehensive obesity care: 6 month real-world outcomes from a digital UK Tier-3 service

JMIR Preprints. 15/01/2026:91452

DOI: 10.2196/preprints.91452

URL: https://preprints.jmir.org/preprint/91452

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