Currently submitted to: JMIR Nursing
Date Submitted: Jan 6, 2026
Open Peer Review Period: Jan 14, 2026 - Mar 11, 2026
(closed for review but you can still tweet)
NOTE: This is an unreviewed Preprint
Warning: This is a unreviewed preprint (What is a preprint?). Readers are warned that the document has not been peer-reviewed by expert/patient reviewers or an academic editor, may contain misleading claims, and is likely to undergo changes before final publication, if accepted, or may have been rejected/withdrawn (a note "no longer under consideration" will appear above).
Peer review me: Readers with interest and expertise are encouraged to sign up as peer-reviewer, if the paper is within an open peer-review period (in this case, a "Peer Review Me" button to sign up as reviewer is displayed above). All preprints currently open for review are listed here. Outside of the formal open peer-review period we encourage you to tweet about the preprint.
Citation: Please cite this preprint only for review purposes or for grant applications and CVs (if you are the author).
Final version: If our system detects a final peer-reviewed "version of record" (VoR) published in any journal, a link to that VoR will appear below. Readers are then encourage to cite the VoR instead of this preprint.
Settings: If you are the author, you can login and change the preprint display settings, but the preprint URL/DOI is supposed to be stable and citable, so it should not be removed once posted.
Submit: To post your own preprint, simply submit to any JMIR journal, and choose the appropriate settings to expose your submitted version as preprint.
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
Mapping the conceptual landscape of Nursing Omics: a theoretical analysis of a multi-omics-inspired framework for nursing informatics
ABSTRACT
Background:
The nursing field is facing unprecedented challenges driven by an explosion of heterogeneous data, persistent data silos, and increasing complexity in clinical decision-making. These issues underscore the urgent need for a systematic, integrative framework to organize and leverage nursing information effectively.
Objective:
This paper aims to conceptualize “Nursing Omics” a novel, multi-omics inspired integrative framework for future-oriented nursing informatics.
Methods:
Using a theoretical development approach, we draw on paradigms from genomics, proteomics, and other omics disciplines, integrating core principles from nursing informatics, systems science, and data science to construct a coherent conceptual architecture.
Results:
We propose a formal definition of Nursing-Omics and introduce a multidimensional integrative framework comprising the Intervenomics, Responsomics, Behaviomics, Exposomics, Experienomics. The framework is grounded in four foundational principles: holism, dynamism, data-driven insight, and individualization.
Conclusions:
Nursing-Omics offers a transformative paradigm for the systematic integration of nursing data, enabling precision decision-making, accelerating knowledge generation, and advancing intelligent, person-centered care. It represents a critical direction for the evolution of nursing informatics in the era of digital health. Clinical Trial: NO
Citation
Request queued. Please wait while the file is being generated. It may take some time.
Copyright
© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.