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Currently accepted at: JMIR Research Protocols

Date Submitted: Dec 30, 2025
Date Accepted: Oct 31, 2026

This paper has been accepted and is currently in production.

It will appear shortly on 10.2196/90538

The final accepted version (not copyedited yet) is in this tab.

The Osaka-Settsu Prospective Cohort Study for Health, Nutrition and Well-being in Community-Dwelling Adult Participants: Study Protocol and Demographics

  • Mikako Yasuoka; 
  • Hyeon-Ki Kim; 
  • Tsukasa Yoshida; 
  • Kan Oishi; 
  • Chiharu Iwasaka; 
  • Takashi Nakagata; 
  • Yui Nakayama; 
  • Hinako Nanri; 
  • Eiichi Yoshimura; 
  • Yoichi Hatamoto; 
  • Yuka Hamada; 
  • Nobuaki Moriyama; 
  • Mai Matsumoto; 
  • Ikuko Kashino; 
  • Miwa Yamaguchi; 
  • Nobuyo Tsuboyama-Kasaoka; 
  • Moeka Harada; 
  • Mieko Nakamura; 
  • Haruka Shibata; 
  • Heiwa Date; 
  • Misaka Kimura; 
  • Ken Sugimoto; 
  • Motohiko Miyachi; 
  • Tomoki Nakaya; 
  • Yuri Miyamoto; 
  • Ryota Akagi; 
  • Haruhisa Fukuda; 
  • Shigeru Inoue; 
  • Mitsuyoshi Yoshida; 
  • Takeshi Kikutani; 
  • Masafumi Ihara; 
  • Kazuki Fukuma; 
  • Hiroshi Murayama; 
  • Yoshinori Fujiwara; 
  • Shosuke Satake; 
  • Hidenori Arai; 
  • Haruki Momma; 
  • Yosuke Yamada; 
  • Rei Ono; 
  • Hidemi Takimoto

ABSTRACT

Background:

In 2024, we launched the Osaka-Settsu Prospective Cohort Study for Health, Nutrition and Well-being (the Osaka-Settsu Study) in Japan. This population-based prospective study aimed to identify the risk factors for lifestyle-related diseases and care given and contribute to precision health care.

Objective:

This cohort profile paper describes the study design and the demographics of the participants.

Methods:

A self-administered questionnaire survey was mailed to registered residents aged ≥ 18 years in Settsu City from February to June 2024. The survey asked the participants about physical activity, nutritional status, well-being, and frailty. The participants will be followed up for the incidence of lifestyle-related diseases, need for support/long-term care certification, emergency transportation, and migration.

Results:

Of the 71,680 self-administered questionnaires distributed, 13,282 were completed. There were 7238 females and 5887 males. Mean age (standard deviation) were 62.1 (17.6) and 60.7 (18.4) years for females and males, respectively. The number of participants was highest in 70-79 year age group for both female and male participants. The body mass index tends to increase with age in female, in contrast, that increased with age, peaked in the 50s, and declined thereafter in male.

Conclusions:

This study is planned to collect information on vital status and conducts follow-up surveys to identify the predictors of functional decline across the course of life. This study provides valuable evidence for the development of strategies to extend a healthy lifespan.


 Citation

Please cite as:

Yasuoka M, Kim HK, Yoshida T, Oishi K, Iwasaka C, Nakagata T, Nakayama Y, Nanri H, Yoshimura E, Hatamoto Y, Hamada Y, Moriyama N, Matsumoto M, Kashino I, Yamaguchi M, Tsuboyama-Kasaoka N, Harada M, Nakamura M, Shibata H, Date H, Kimura M, Sugimoto K, Miyachi M, Nakaya T, Miyamoto Y, Akagi R, Fukuda H, Inoue S, Yoshida M, Kikutani T, Ihara M, Fukuma K, Murayama H, Fujiwara Y, Satake S, Arai H, Momma H, Yamada Y, Ono R, Takimoto H

The Osaka-Settsu Prospective Cohort Study for Health, Nutrition and Well-being in Community-Dwelling Adult Participants: Study Protocol and Demographics

JMIR Research Protocols. 31/10/2026:90538 (forthcoming/in press)

DOI: 10.2196/90538

URL: https://preprints.jmir.org/preprint/90538

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