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Currently submitted to: JMIR mHealth and uHealth

Date Submitted: Feb 24, 2026
Open Peer Review Period: Feb 25, 2026 - Apr 22, 2026
(currently open for review)

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Mobile Apps for Neonatal Jaundice Screening in Low- and Middle-Income Countries: A Scalable and Sustainable Solution?

  • Jesús Elizarrarás-Rivas; 
  • Gabriela Jiménez-Díaz; 
  • Raquel Elizarrarás-Cruz; 
  • Héctor Alejandro Cabrera-Fuentes; 
  • Eduardo Perez-Campos; 
  • Jennifer J. Infanti

ABSTRACT

Neonatal jaundice remains a preventable cause of neurological damage in low- and middle-income countries, where limitations in infrastructure and staffing make timely screening difficult. Mobile technologies, such as the Picterus Jaundice Pro (JP) app, offer a promising alternative by enabling bilirubin estimation from digital images using algorithms and calibration cards. In this viewpoint, we explore the feasibility, clinical validation, and barriers to adopting this tool in resource-limited settings, particularly in Latin America. The Mexican experience is presented as a reference for the gradual integration of mHealth technologies into public systems, highlighting both opportunities and regulatory, operational, and cultural challenges. Available evidence supports its utility; however, scaling will depend on political will, sustained financing, and clear regulatory frameworks. Picterus JP may represent a strategic step toward equity in neonatal health.


 Citation

Please cite as:

Elizarrarás-Rivas J, Jiménez-Díaz G, Elizarrarás-Cruz R, Cabrera-Fuentes HA, Perez-Campos E, Infanti JJ

Mobile Apps for Neonatal Jaundice Screening in Low- and Middle-Income Countries: A Scalable and Sustainable Solution?

JMIR Preprints. 24/02/2026:89976

DOI: 10.2196/preprints.89976

URL: https://preprints.jmir.org/preprint/89976

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