JMIR Publications

ABSTRACT

Background:

Abstract

Background:

Cardiac implantable electronic devices are crucial in managing various cardiac conditions, but their monitoring poses considerable challenges. Algorithm-enabled remote monitoring of these devices has emerged as a promising solution to enhance patient outcomes and potentially reduce healthcare expenditures, though its economic impact remains under-explored.

Objective:

This systematic review protocol aims to contribute new knowledge by evaluating the cost-effectiveness and cost-utility of algorithm-enabled remote monitoring for cardiac implantable electronic devices in patients with or at risk of heart failure, providing a synthesis of existing economic evidence.

Methods:

The search of literature will be performed on MEDLINE, EMBASE, Scopus, Web of Science, Cochrane Library, with supplementary searches in NHS EED, NICE, CADTH, INAHTA, and NIHR. This protocol is reported in accordance with PRISMA-P 2015, and the completed review will be reported following PRISMA 2020.

Results:

Following database searching and de-duplication, 3,108 records were retrieved; 731 duplicates were removed, leaving 2,377 records for title and abstract screening. The review will identify and synthesise economic evaluations of algorithm-enabled remote monitoring in adults with cardiac implantable electronic devices, summarising reported costs, outcomes, and cost-effectiveness results. Methodological quality, risk of bias, and sources of heterogeneity across studies will be assessed.

Conclusions:

Findings of this review could directly inform healthcare providers, policymakers, and device manufacturers about the economic value proposition of these advanced monitoring systems, facilitating evidence-based decision-making in resource allocation and technological adoption. Clinical Trial: PROSPERO registration ID [CRD420251179324]