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Accepted for/Published in: JMIR Mental Health

Date Submitted: Dec 18, 2025
Date Accepted: Feb 26, 2026

The final, peer-reviewed published version of this preprint can be found here:

Efficacy of a World Health Organization–Guided Self-Help Intervention for Reducing Psychological Distress in Afghan Refugees: Randomized Controlled Trial

Nickerson A, Kurt G, Specker P, Camilleri A, Susanty D, Argadianti R, Keegan D, Nandyatama R, Yuanita A, Hermawan APR, Bryant R, O'Donnell M, Rafei M, Bayani R, Liddell B

Efficacy of a World Health Organization–Guided Self-Help Intervention for Reducing Psychological Distress in Afghan Refugees: Randomized Controlled Trial

JMIR Ment Health 2026;13:e89928

DOI: 10.2196/89928

PMID: 42160742

PMCID: 13189532

The efficacy of a WHO guided self-help intervention for reducing psychological distress in Afghan refugees: A randomized controlled trial

  • Angela Nickerson; 
  • Gulsah Kurt; 
  • Philippa Specker; 
  • Anna Camilleri; 
  • Dessy Susanty; 
  • Rizka Argadianti; 
  • David Keegan; 
  • Randy Nandyatama; 
  • Atika Yuanita; 
  • Angga Putra Reynady Hermawan; 
  • Richard Bryant; 
  • Meaghan O'Donnell; 
  • Mahdi Rafei; 
  • Rahmatullah Bayani; 
  • Belinda Liddell

ABSTRACT

Background:

Common mental health disorders are highly prevalent among refugees. Prior research has shown the effectiveness of scalable, task-shared, psychological interventions in improving refugee mental health and wellbeing. There is a lack of research on the effectiveness of individually supported, self-help interventions for refugees in low-resource, transit settings.

Objective:

The current study aimed to test the efficacy of an individually-supported self-help stress-management intervention developed by the World Health Organization - Doing What Matters in Times of Stress- in reducing psychological distress and improving functioning among refugees in Indonesia, a major transit country in the Asia-Pacific region.

Methods:

A single-blind randomized controlled trial with 303 Farsi-speaking refugees was conducted between June 2024 and June 2025. Participants with moderate to high psychological distress (Kessler Psychological Distress Scale, K10 ≥ 20) were randomly allocated to the facilitator-guided individual DWM condition (N = 202) or a repeated assessment control (RAC) condition (N = 101). The primary outcome was psychological distress (K10) at the post-treatment assessment. Secondary outcomes were PTSD symptoms, functional impairment, social functioning and personally identified problems.

Results:

Intent-to-treat analysis indicated that participants in the DWM condition showed greater reductions in K10 than those in RAC (β = -0.563, SE = 0.124, p<.001, Cohen’s d = 0.56 at post-treatment, β = -0.447, SE = 0.140, p =.002, Cohen’s d= 0.45 at 1-month follow-up). Similarly, those participants in the DWM condition reported greater improvements in PTSD symptoms, wellbeing, social functioning, functional impairment, and personally identified psychological problems. No serious adverse events were reported.

Conclusions:

The findings provide the first evidence for the effectiveness of DWM in reducing psychological distress and improving overall functioning among urban refugees living in a transit setting. Individually-supported self-help interventions such as DWM might offer an effective, feasible, and scalable approach to improving mental health for refugees. Clinical Trial: ACTRN12624000609550


 Citation

Please cite as:

Nickerson A, Kurt G, Specker P, Camilleri A, Susanty D, Argadianti R, Keegan D, Nandyatama R, Yuanita A, Hermawan APR, Bryant R, O'Donnell M, Rafei M, Bayani R, Liddell B

Efficacy of a World Health Organization–Guided Self-Help Intervention for Reducing Psychological Distress in Afghan Refugees: Randomized Controlled Trial

JMIR Ment Health 2026;13:e89928

DOI: 10.2196/89928

PMID: 42160742

PMCID: 13189532

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