Accepted for/Published in: JMIR Research Protocols
Date Submitted: Dec 17, 2025
Open Peer Review Period: Dec 17, 2025 - Feb 11, 2026
Date Accepted: May 18, 2026
(closed for review but you can still tweet)
A One Health Scoping Review of Cryptosporidium in Southeast Asia: Mapping Prevalence, Diagnostics, and Evidence Gaps Across Human, Animal, and Environmental Domains – A Protocol
ABSTRACT
Background:
Cryptosporidium is a protozoan parasite of global importance that causes diarrheal disease in both humans and animals. In Southeast Asia, ecological diversity, agricultural expansion, and uneven infrastructure create a complex landscape for disease transmission. Although numerous studies exist, no comprehensive review has examined environmental, foodborne, and socioeconomic factors through an integrated One Health lens.
Objective:
To describe the methodology for a scoping review that maps research on Cryptosporidium in Southeast Asia, focusing on prevalence, diagnostic approaches, and transmission determinants across human, animal, and environmental domains.
Methods:
The review follows Arksey and O’Malley’s framework, refined by Levac et al. and the Joanna Briggs Institute. Five databases were searched using broad organism- and geography-based terms. Screening and data extraction were conducted in Covidence with predefined criteria. Descriptive synthesis and thematic mapping will be performed in RStudio. The protocol is registered on the Open Science Framework.
Results:
Early observations indicate geographic gaps and limited application of One Health frameworks constraining understanding of Cryptosporidium ecology in Southeast Asia.
Conclusions:
This review will identify research gaps, variations in diagnostic methods, and opportunities for integrated surveillance and control. Findings will inform future research priorities and support multidisciplinary approaches under the One Health framework.
Citation
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Copyright
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