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Accepted for/Published in: JMIR Infodemiology

Date Submitted: Dec 16, 2025
Date Accepted: Mar 28, 2026

The final, peer-reviewed published version of this preprint can be found here:

Exploring Weight Loss Medication Discourse: Mixed Methods Analysis of US-Based Facebook Posts

Dennard E, Makres K, Alibilli A, Jain V, Wang A, Abim-Karmon R, Criss S, Hswen Y, Nguyen Q, Ratzki-Leewing A, McCoy R, Nguyen T

Exploring Weight Loss Medication Discourse: Mixed Methods Analysis of US-Based Facebook Posts

JMIR Infodemiology 2026;6:e89732

DOI: 10.2196/89732

PMID: 42099097

PMCID: 13153451

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Exploring Weight Loss Medication Discourse: A Mixed-Methods Analysis of U.S.-Based Facebook Posts

  • Elizabeth Dennard; 
  • Katrina Makres; 
  • Amrutha Alibilli; 
  • Vidur Jain; 
  • Anne Wang; 
  • Roger Abim-Karmon; 
  • Shaniece Criss; 
  • Yulin Hswen; 
  • Quynh Nguyen; 
  • Alexandria Ratzki-Leewing; 
  • Rozalina McCoy; 
  • Thu Nguyen

ABSTRACT

Background:

Despite the documented clinical efficacy of weight loss medications, few large-scale mixed methods studies have captured the experiences of individuals taking these medications.

Objective:

BERTopic Modeling was used to identify latent topics, followed by a qualitative thematic analysis to gain a better understanding of how the public views and interacts with weight loss medications online.

Methods:

We utilized CrowdTangle to collect 2,500 United States-based Facebook posts from January 1, 2022, to May 31, 2024. BERTopic Modeling was used to identify latent topics, followed by a qualitative thematic analysis to gain a better understanding of how the public views and interacts with weight loss medications online.

Results:

An analysis of 2,500 Facebook posts revealed distinct thematic patterns across five unique subcategories: 1) healthy weight management, 2) weight loss medications, 3) discussion specific to Semaglutide, 4) discussion specific to Ozempic, and 5) public figures and media. Thirteen overarching themes emerged through this thematic analysis, with the most common themes including weight management programs (n = 702), neutral content linked to weight loss medication use (n = 466), harms of weight loss medication use (n = 373), benefits of weight loss medication use (n = 329), and access to these medications (n = 188).

Conclusions:

Social media offers critical insights into individual experiences with pharmacotherapy and weight management. Enhanced public education may optimize the safe use of GLP-1 RAs for weight loss.


 Citation

Please cite as:

Dennard E, Makres K, Alibilli A, Jain V, Wang A, Abim-Karmon R, Criss S, Hswen Y, Nguyen Q, Ratzki-Leewing A, McCoy R, Nguyen T

Exploring Weight Loss Medication Discourse: Mixed Methods Analysis of US-Based Facebook Posts

JMIR Infodemiology 2026;6:e89732

DOI: 10.2196/89732

PMID: 42099097

PMCID: 13153451

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