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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Dec 2, 2025
Date Accepted: Jun 2, 2026

The final, peer-reviewed published version of this preprint can be found here:

Large Language Model Summarization of Physician-to-Physician Calls for Interhospital Transfer of Patients With ST-Elevation Myocardial Infarction: Observational Study

Wrenn JO, Behrens M, Hershey MS, Maldaver M, Mitchell J, Thompson T, Triana AJ, Virk ZM, Akdas Y, Cauley MR, Ward MJ, Monahan K

Large Language Model Summarization of Physician-to-Physician Calls for Interhospital Transfer of Patients With ST-Elevation Myocardial Infarction: Observational Study

J Med Internet Res 2026;28:e88834

DOI: 10.2196/88834

PMID: 42348906

Large Language Model Summarization of Physician-to-Physician Calls for Interhospital Transfer of Patients with ST-Elevation Myocardial Infarction: Observational Study

  • Jesse O. Wrenn; 
  • Madelaine Behrens; 
  • Mary S. Hershey; 
  • Marc Maldaver; 
  • John Mitchell; 
  • Trevor Thompson; 
  • Austin J. Triana; 
  • Zain M. Virk; 
  • Yasemin Akdas; 
  • Michael R. Cauley; 
  • Michael J Ward; 
  • Ken Monahan

ABSTRACT

Background:

Transfer of patients with suspected ST-elevation myocardial infarction (STEMI) requires timely and robust communication, but clinical uptake of potentially useful information from physician-to-physician phone calls authorizing transfer is low, at least in part due to relative inaccessibility.

Objective:

We sought to evaluate whether large language models (LLMs) can effectively summarize these transfer calls, which could facilitate access to valuable information for receiving physicians.

Methods:

STEMI transfer calls for which our institution was the receiving facility were transcribed and summarized by OpenAI Whisper and ChatGPT software, respectively. Each summary was reviewed by two of seven independent physician-raters. Summaries were rated using the Likert Scale applied to an eight-domain framework adapted from the Physician Document Quality Instrument. In addition, we calculated raw inter-rater agreement for each domain across all summaries.

Results:

Exact agreement between raters was 62%, and 90% of paired ratings were within one point of each other. The mean rating of all summaries across all domains was 4.6 out of 5. Sixty-five percent of summaries had mean ratings of >4/5 on all eight domains. The ‘useful’ (4.84/5) and ‘consistent’ (4.85/5) domains were highest rated, and the ‘thorough’ (4.42/5) and ‘hallucination’ (4.40/5) domains were lowest rated.

Conclusions:

This proof-of-concept study suggests that LLMs can generate accurate and pertinent summaries of interhospital transfer calls for STEMI patients. Areas for future investigation include assessing the impact of these summaries on clinical outcomes, expanding to other patient populations, and applying this approach to additional clinical scenarios in which physician-to-physician communication plays a significant role.


 Citation

Please cite as:

Wrenn JO, Behrens M, Hershey MS, Maldaver M, Mitchell J, Thompson T, Triana AJ, Virk ZM, Akdas Y, Cauley MR, Ward MJ, Monahan K

Large Language Model Summarization of Physician-to-Physician Calls for Interhospital Transfer of Patients With ST-Elevation Myocardial Infarction: Observational Study

J Med Internet Res 2026;28:e88834

DOI: 10.2196/88834

PMID: 42348906

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