JMIR Publications

ABSTRACT

Background:

Fractional radiofrequency microneedling (FRM) is an effective non-surgical facelift modality supported by growing clinical evidence. While generally well tolerated, post-procedural erythema, pain, swelling and bruising typically last up to 7 days. Other serious complications include prolonged swelling, infection, persistent grid mark, burns and hypo- or hyperpigmentation. Recombinant human collagen has demonstrated potent wound-healing and anti-inflammatory properties, which could be harnessed for post-FRM recovery.

Objective:

To date, there is a lack of published studies evaluating the use of topical agents to improve post-procedural recovery following FRM. This case report aims to address this gap by describing the early experience using topical recombinant collagen post-FRM for non-surgical facelift.

Methods:

Two 40-year-old female patients, with Fitzpatrick skin type IV, underwent FRM for non-surgical facelift. The procedure was performed with standard settings of energy. Immediately post-procedure, topical recombinant collagen was applied to the treated areas. Either clinical photography and/or cross-polarized imaging were used to objectively capture the changes in facial erythema and swelling.

Results:

Case 1 demonstrated near-complete resolution of erythema and discomfort within one hour after serum application. Case 2 showed results captured by cross-polarized imaging within two hours. No adverse events were reported and both patients tolerated the procedure well.

Conclusions:

These preliminary observations have suggested that topical recombinant collagen may promote accelerated post-procedural recovery after FRM.