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Accepted for/Published in: Interactive Journal of Medical Research

Date Submitted: Oct 29, 2025
Open Peer Review Period: Oct 29, 2025 - Nov 10, 2025
Date Accepted: Sep 3, 2026
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

The Shifting Landscape of Natural Health Product Licensing in Canada: The e-Commerce Case of Stem Cell Supplements

Marcon A, Jewer M, Caulfield T

The Shifting Landscape of Natural Health Product Licensing in Canada: The e-Commerce Case of Stem Cell Supplements

Interact J Med Res 2026;15:e86747

DOI: 10.2196/86747

PMID: 42804752

The shifting landscape of natural health product licensing in Canada: The ecommerce case of stem cell supplements

  • Alessandro Marcon; 
  • Michael Jewer; 
  • Timothy Caulfield

ABSTRACT

Natural health product (NHP) regulations have shifted in Canada with the aim of reducing "red tape" and enabling market entry. This study assessed how many "stem cell" supplements for sale on Amazon.ca had Health-Canada required Natural Product Number (NPN) licences compared with Vitamin D and "longevity" supplements. It also conducted an marketing overview analysis comparing the Amazon.ca discourse across the three product types. Findings show a gap in regulatory licensing compliance between "stem cell" supplements compared to Vitamin D or "longevity" supplements." Marketing discourse also presented potential conflict with regulatory parameters. We discuss the impacts of loosening NHP regulations, and the potential for products with weak evidentiary bases to enhance validation through NPN licensing.


 Citation

Please cite as:

Marcon A, Jewer M, Caulfield T

The Shifting Landscape of Natural Health Product Licensing in Canada: The e-Commerce Case of Stem Cell Supplements

Interact J Med Res 2026;15:e86747

DOI: 10.2196/86747

PMID: 42804752

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