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Currently accepted at: JMIR Research Protocols

Date Submitted: Oct 22, 2025
Date Accepted: Aug 6, 2026

This paper has been accepted and is currently in production.

It will appear shortly on 10.2196/86345

The final accepted version (not copyedited yet) is in this tab.

Study protocol for remote longitudinal tracking of sleep, depression, and cognition across early adolescence

  • Katharine C. Simon; 
  • Lia Galut; 
  • Spencer Polk; 
  • Shun Iwata; 
  • Mahyar Abbasian; 
  • Amir Rahmani; 
  • Uma Rao; 
  • Jessica Borelli; 
  • Sara C. Mednick

ABSTRACT

Depression in adolescents is a growing public health concern, with 3.5 million youth in the United States experiencing a depressive episode each year. When symptoms emerge in early adolescence, they can have lasting psychological, physical, and cognitive consequences, highlighting the urgent need for proactive intervention. Insufficient sleep—characterized by short duration, irregular timing, and poor quality—is bidirectionally linked to depression and associated with impaired cognitive performance. This protocol examines how insufficient sleep and depressive symptoms interact to shape longitudinal cognitive trajectories, addressing a critical gap in understanding the dynamic associations among sleep, mood, and cognition. By identifying key developmental periods of vulnerability and resilience, this protocol will collect the data required to inform future sleep-based interventions that can promote mental health and optimize cognitive outcomes across early adolescence.


 Citation

Please cite as:

Simon KC, Galut L, Polk S, Iwata S, Abbasian M, Rahmani A, Rao U, Borelli J, Mednick SC

Study protocol for remote longitudinal tracking of sleep, depression, and cognition across early adolescence

JMIR Research Protocols. 06/08/2026:86345 (forthcoming/in press)

DOI: 10.2196/86345

URL: https://preprints.jmir.org/preprint/86345

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