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Accepted for/Published in: JMIR Medical Informatics

Date Submitted: Oct 13, 2025
Date Accepted: Jun 3, 2026

The final, peer-reviewed published version of this preprint can be found here:

Pre-Amyloidosis Red-Flag Clinical Diagnoses in Light Chain (AL) Versus Age-Related Transthyretin (ATTRwt) Amyloidosis: Electronic Health Record–Based Descriptive Study

Estrada-Merly N, Pezzin LE, Sparapani R, D'Souza A

Pre-Amyloidosis Red-Flag Clinical Diagnoses in Light Chain (AL) Versus Age-Related Transthyretin (ATTRwt) Amyloidosis: Electronic Health Record–Based Descriptive Study

JMIR Med Inform 2026;14:e85803

DOI: 10.2196/85803

PMID: 42330197

Pre-amyloidosis red-flag clinical diagnoses in light chain (AL) versus age related transthyretin (ATTRwt) amyloidosis: Electronic Health Record–based descriptive study

  • Noel Estrada-Merly; 
  • Liliana E. Pezzin; 
  • Rodney Sparapani; 
  • Anita D'Souza

ABSTRACT

This study analyzed electronic health records to identify distinct early clinical patterns in AL and ATTRwt amyloidosis, highlighting opportunities for earlier diagnosis through red-flag symptom recognition.


 Citation

Please cite as:

Estrada-Merly N, Pezzin LE, Sparapani R, D'Souza A

Pre-Amyloidosis Red-Flag Clinical Diagnoses in Light Chain (AL) Versus Age-Related Transthyretin (ATTRwt) Amyloidosis: Electronic Health Record–Based Descriptive Study

JMIR Med Inform 2026;14:e85803

DOI: 10.2196/85803

PMID: 42330197

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