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Accepted for/Published in: Online Journal of Public Health Informatics

Date Submitted: Oct 10, 2025
Date Accepted: May 12, 2026

The final, peer-reviewed published version of this preprint can be found here:

Tweets Surrounding Pharmaceutical Drug Brands With Top Direct-to-Consumer TV-Advertising Budgets: Social Media Listening Study

Macias W, Navarro Castillo MB

Tweets Surrounding Pharmaceutical Drug Brands With Top Direct-to-Consumer TV-Advertising Budgets: Social Media Listening Study

Online J Public Health Inform 2026;18:e85641

DOI: 10.2196/85641

PMID: 42314149

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Top Direct-to-Consumer TV Advertising Budgets and Their Pharmaceutical Drug Brand Conversations on Twitter: A Social Media Listening Study

  • Wendy Macias; 
  • María Belén Navarro Castillo

ABSTRACT

Direct-to-consumer (DTC) pharmaceutical advertising allots billions annually in the U.S., yet social media discourse of it remains underexamined. This social listening study employs Brandwatch to analyze Twitter conversations (August 2021—August 2023) surrounding top-budgeted DTC brands. A dataset of 44,700 mentions from 26,800 unique authors was analyzed for content, sentiment, and thematic relevance using uses gratifications and agenda-setting frameworks. Four dominant themes emerged: (1) patient experiences/testimonials, (2) drug pricing/insurance concerns, (3) pharmaceutical news, and (4) advertising commentary. Implications surround public policy and industry practice. Suggested future research directions include NodeXL network analysis and qualitative inquiry into user motivations.


 Citation

Please cite as:

Macias W, Navarro Castillo MB

Tweets Surrounding Pharmaceutical Drug Brands With Top Direct-to-Consumer TV-Advertising Budgets: Social Media Listening Study

Online J Public Health Inform 2026;18:e85641

DOI: 10.2196/85641

PMID: 42314149

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