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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Oct 10, 2025
Open Peer Review Period: Oct 13, 2025 - Dec 8, 2025
Date Accepted: Feb 4, 2026
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

AI-Enabled Wearables for Motor Function Assessment and Rehabilitation in Parkinson Disease: Scoping Review

Li S, Chen S, Yu X, Shang H, Tu T, Quan M

AI-Enabled Wearables for Motor Function Assessment and Rehabilitation in Parkinson Disease: Scoping Review

J Med Internet Res 2026;28:e85596

DOI: 10.2196/85596

PMID: 41746703

PMCID: 12982951

AI-Enabled Wearables for Motor Function Assessment and Rehabilitation in Parkinson’s Disease: A Scoping Review and Evidence Map

  • Shengting Li; 
  • Siqi Chen; 
  • Xiaosong Yu; 
  • Huixiang Shang; 
  • Tingting Tu; 
  • Mingtao Quan

ABSTRACT

Background:

Artificial intelligence (AI)–driven wearable technologies are rapidly emerging in rehabilitation and functional assessment for patients with Parkinson’s disease (PD). However, evidence remains fragmented, integration into nursing practice is limited, and comprehensive synthesis is lacking.

Objective:

To summarize studies on AI-enabled wearable devices for PD rehabilitation and assessment, describing device types, monitored indicators, algorithms, and application characteristics, and identifying research gaps and barriers to clinical translation.

Methods:

Following the PRISMA-ScR guidelines, nine databases (CNKI, Wanfang, SinoMed, Cochrane Library, PubMed, Web of Science, CINAHL, Scopus, and Embase) were searched for original studies involving PD patients using AI-integrated wearable devices for rehabilitation, assessment, or monitoring. Two reviewers independently screened, extracted, and synthesized data to construct an evidence map.

Results:

A total of 1,402 records were initially retrieved, and 61 studies were included after deduplication and screening. Devices comprised sensor modules (wearable IMUs), smartwatches/wristbands, and smart insoles. Multi-sensor systems accounted for 77.05%, with accelerometers most common (95.08%) and signals predominantly collected passively (77.05%). Studies were mainly clinical or laboratory based, with single- or multi-session designs. Leave-one-out (47.54%) and k-fold (42.62%) cross-validation predominated, while external validation was scarce (4.92%). Sensitivity (65.57%) and accuracy (62.30%) were the most frequently reported metrics, indicating methodological and metric heterogeneity.

Conclusions:

AI-enabled wearables show promise for PD rehabilitation and remote assessment but remain detection-heavy with limited closed-loop implementation. Real-world, multicenter, and longitudinal evidence is sparse, and external validation and calibration are rarely performed. Future work should expand to non-motor and multimodal signals, routinely apply external validation and decision-curve analysis, and enhance standardization and interoperability. Developing closed-loop rehabilitation pathways that integrate assessment, intervention, feedback, and re-evaluation in home and community contexts to enhance clinical applicability and scalability.


 Citation

Please cite as:

Li S, Chen S, Yu X, Shang H, Tu T, Quan M

AI-Enabled Wearables for Motor Function Assessment and Rehabilitation in Parkinson Disease: Scoping Review

J Med Internet Res 2026;28:e85596

DOI: 10.2196/85596

PMID: 41746703

PMCID: 12982951

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