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Currently submitted to: JMIR Formative Research

Date Submitted: Oct 13, 2025
Open Peer Review Period: Oct 28, 2025 - Dec 23, 2025
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Effects of an Integrated Mobile Application with Telemedicine on Weight Management and Health Behaviors in Obese Adults: A Pilot Study

  • Chiao-Lin Hsu; 
  • Cai-Sin Yao; 
  • Pin-Chieh Wu; 
  • Wei-Chin Huang; 
  • Chi-Shen Chen; 
  • Kuang-Chieh Hsueh; 
  • Hsien-Chung Yu

ABSTRACT

Background:

Obesity is associated with numerous health issues, and early identification and intervention in high-risk individuals can improve prognosis.

Objective:

This study evaluated the impact and effectiveness of an integrated health management program on the weight of individuals with obesity.

Methods:

We retrospectively collected case management data from 97 individuals with obesity (≥20 years) who received weight management care between September 1, 2023, and April 30, 2024. Exclusions included weight-loss medications, surgery, and other weight-loss programs. Data comprised patient demographics, medical history, health behaviors, and physical examination results. Follow-up data were obtained from a health management platform and hospital database. Statistical analyses used paired t-tests, Wilcoxon signed-rank tests, and generalized estimating equations (GEE).

Results:

The 2-month completers achieved a greater weight loss (−0.87 ± 1.35 kg) than 1-month completers (−0.03 ± 0.75 kg; p < 0.001). Health behavior scores improved at both time points (all p < 0.001), and step counts increased 8.9-fold overall and 10.5-fold among 2-month completers (p < 0.001). Among 2-month completers, those engaging in ≥3 program components had a lower adjusted weight (86.0 ± 1.6 kg) than those engaging in <3 program components (89.3 ± 1.7 kg; F = 6.09, p = 0.017). GEE models showed that ≥3-component engagement increased odds of weight loss by 16.6-fold at 1 month and 23.2-fold at 2 months.

Conclusions:

Weight loss improved in a dose-dependent manner, with ≥3-component engagement showing the strongest effects. Long-term studies with booster contacts are needed to validate the sustained benefits of our integrated health management program. Clinical Trial: none


 Citation

Please cite as:

Hsu CL, Yao CS, Wu PC, Huang WC, Chen CS, Hsueh KC, Yu HC

Effects of an Integrated Mobile Application with Telemedicine on Weight Management and Health Behaviors in Obese Adults: A Pilot Study

JMIR Preprints. 13/10/2025:85529

DOI: 10.2196/preprints.85529

URL: https://preprints.jmir.org/preprint/85529

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