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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Sep 30, 2025
Open Peer Review Period: Oct 1, 2025 - Nov 26, 2025
Date Accepted: Jan 20, 2026
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Psychosis Risk and Generative Artificial Intelligence Use Frequency, Motivations, and Delusion-Like Experiences: Cross-Sectional Survey Study

Buck BE, Maheux AJ

Psychosis Risk and Generative Artificial Intelligence Use Frequency, Motivations, and Delusion-Like Experiences: Cross-Sectional Survey Study

J Med Internet Res 2026;28:e85038

DOI: 10.2196/85038

PMID: 41785452

Generative AI use and psychosis risk: A cross-sectional survey of usage frequency, motivations, and delusion-like experiences

  • Benjamin Edwards Buck; 
  • Anne Julia Maheux

ABSTRACT

Background:

We conducted a large-scale cross-sectional survey of N = 1004 U.S. young adults (Mage = 22.68, 56.4% women, 46.8% White, 16.6% Black, 14.8% Latine, 11.4% Asian), divided the sample of individuals that had used genAI into “elevated risk” (PQ-B Distress Score ≥ 20; N = 267, 28.0%) and “low risk” groups (PQ-B Distress Score < 20; N = 685, 72.0%), and compared groups on several assessments related to genAI use.

Objective:

We aimed to evaluate associations of psychosis risk to genAI use frequency, motivations for use, and genAI interactions involving potential delusions.

Methods:

We conducted a large-scale cross-sectional survey of N = 1004 U.S. young adults (Mage = 22.68, 56.4% women, 46.8% White, 16.6% Black, 14.8% Latine, 11.4% Asian), divided the sample of individuals that had used genAI into “elevated risk” (PQ-B Distress Score ≥ 20; N = 267, 28.0%) and “low risk” groups (PQ-B Distress Score < 20; N = 685, 72.0%), and compared groups on several assessments related to genAI use.

Results:

We found that while members of the elevated risk group were no more likely to have ever used genAI, they were significantly more likely to report aberrantly high use (i.e. several times per day, more than 30 minutes per day, six or more chatbot conversations per day). Those at elevated risk were more likely to report using genAI to receive social and emotional support and significantly more likely to ascribe human-like roles to their chatbot interactions (e.g. companion, friend, therapist, and romantic partner). Delusion-like experiences and interactions were also much more likely to be reported among those at risk for psychosis.

Conclusions:

GenAI chatbots may play a role in shifting symptom-related experiences among young adults at risk. While this cross-sectional study does not assess the causal impact of genAI on symptoms, it highlights the importance of intentional design of these systems to limit risks and maximize benefits for individuals at risk for psychosis.


 Citation

Please cite as:

Buck BE, Maheux AJ

Psychosis Risk and Generative Artificial Intelligence Use Frequency, Motivations, and Delusion-Like Experiences: Cross-Sectional Survey Study

J Med Internet Res 2026;28:e85038

DOI: 10.2196/85038

PMID: 41785452

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