Currently accepted at: Interactive Journal of Medical Research
Date Submitted: Sep 19, 2025
Date Accepted: Jul 2, 2026
This paper has been accepted and is currently in production.
It will appear shortly on 10.2196/84466
The final accepted version (not copyedited yet) is in this tab.
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
Comparative Analysis of Cardiometabolic Risk Profiles Among Hypertensive and Non-Hypertensive Adults in Johannesburg, South Africa
ABSTRACT
Background:
Hypertension is a significant modifiable risk factor for cardiometabolic syndrome, leading to increased morbidity and premature mortality. Understanding the differences in cardiometabolic risk profiles between hypertensive and normotensive adults is essential for effective prevention strategies. This study examined these risks among adults in Johannesburg South, Gauteng Province, South Africa.
Objective:
This study examined these risks among adults in Johannesburg South, Gauteng Province, South Africa.
Methods:
A cross-sectional study was conducted with 209 adults aged 25 to 65 years, recruited from three Johannesburg townships in Region G. Anthropometric measures (BMI, waist circumference), blood pressure, and biochemical indices (random glucose, total cholesterol, HDL-C, LDL-C, triglycerides) were assessed. Statistical analyses were performed using STATA version 19, with a significance level of p < 0.05.
Results:
Hypertension prevalence increased significantly with BMI and waist circumference. However, age and elevated glucose levels were the only independent predictors of hypertension. Specifically, each additional year of age raised the odds of hypertension by 7% (OR = 1.08; 95% CI: 1.05–1.11; p < 0.001).
Conclusions:
Hypertension in this population is significantly influenced by age, obesity, central adiposity, and high glucose levels.
Citation
Request queued. Please wait while the file is being generated. It may take some time.
Copyright
© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.