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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Sep 19, 2025
Open Peer Review Period: Sep 19, 2025 - Nov 14, 2025
Date Accepted: Feb 27, 2026
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Large Language Model–Generated Patient Instructions for Prescriptions in Primary Health Care: Preclinical Algorithm Validation

Silveira Nogueira Reis Z, Tuler Albergaria E, Silvina Pagano A, Martins Lage E, Ribeiro de Oliveira F, dos Santos Dias C, Almeida Oliveira J, Miranda Varella Pereira G, Jose Ramos de Oliveira I, Franco Mineiro Ã, Carvalho Lima Oliveira I, dos Reis de Jesus D, Pereira de Souza Júnior A, de Carvalho Gomes I, André Cuevas Gaete R, Cruz-Correia R, Chaves Dutra da Rocha L

Large Language Model–Generated Patient Instructions for Prescriptions in Primary Health Care: Preclinical Algorithm Validation

J Med Internet Res 2026;28:e84444

DOI: 10.2196/84444

PMID: 42190235

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

PDF not available

Per the author's request this version is not available.