Accepted for/Published in: JMIR Formative Research
Date Submitted: Sep 8, 2025
Open Peer Review Period: Sep 8, 2025 - Nov 3, 2025
Date Accepted: Feb 16, 2026
(closed for review but you can still tweet)
Validity of a smartphone-based measurement for assessing lower limb power for sarcopenia and frailty discrimination: The Otassha Study
ABSTRACT
Background:
Increasing life expectancy has increased focus on health-related consequences of aging, such as sarcopenia and frailty. Given their prevalence among older individuals and frequent long-term care needs, early detection and intervention are crucial.
Objective:
To validate a novel smartphone-based system measuring acceleration during the sit-to-stand movement to detect sarcopenia and frailty.
Methods:
The study included 556 participants from the 2011 Otassha study cohort who underwent health checkups in 2023. A smartphone application, complemented by auditory prompts from a Bluetooth speaker, recorded acceleration at 60 Hz as participants performed sit-to-stand movements twice. Sarcopenia and frailty were classified using the Asian Working Group for Sarcopenia 2019 consensus and revised Japanese version of the Cardiovascular Health Study criteria, respectively. Logistic regression with stepwise variable reduction was used to develop sarcopenia and frailty predictive models, including variables of peak force (f), time from the start of movement to peak acceleration (t1), time from peak acceleration to attainment of a stable stance (t2), sex, age, and weight.
Results:
We identified 95 participants with sarcopenia (25 men and 70 women) and 51 with frailty (22 men and 29 women). Sarcopenia and frailty predictive models exhibited robust areas under receiver operating characteristic curves of 0.821 and 0.741, respectively.
Conclusions:
Smartphone accelerometers can assess lower-extremity power reliably and contribute to sarcopenia and frailty diagnoses. The predictive models, suitable for home use, could aid in early detection of and intervention for these conditions, underscoring the growing utility of smartphone-based diagnostics for addressing age-related health concerns.
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© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.