Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: JMIR Formative Research

Date Submitted: Sep 18, 2025
Date Accepted: Oct 15, 2026

The final, peer-reviewed published version of this preprint can be found here:

Internet-Based Cognitive Behavioral Therapy for Panic Disorder Among Arabic-Speaking Patients: Case Series

Halaj A, Kaiyal L, Andersson G, Andersson G, Huppert JD

Internet-Based Cognitive Behavioral Therapy for Panic Disorder Among Arabic-Speaking Patients: Case Series

JMIR Form Res 2026;10:e83415

DOI: 10.2196/83415

PMID: 43019539

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Internet-Based Cognitive Behavioral Therapy for Arabic-Speaking Patients with Panic Disorder

  • Asala Halaj; 
  • Lama Kaiyal; 
  • Gerhard Andersson; 
  • Gerhard Andersson; 
  • Jonathan D Huppert

ABSTRACT

Background:

Internet-based cognitive behavior therapy (ICBT) has proven effective for anxiety disorders, including panic disorder (PD), but research on its effectiveness across cultures and languages is limited.

Objective:

This study explored the effectiveness of ICBT for PD in Arabic and investigated potential cultural differences in anxiety sensitivity (AS) between Arabic and Hebrew speakers in Israel.

Methods:

Six Arabic-speaking patients received ICBT. Assessments of PD symptoms, AS, and agoraphobic avoidance were conducted pre-treatment, weekly, post-treatment, and at 3-month follow-up.

Results:

Results were compared with Hebrew-speaking patients from a previous study. Four patients completed treatment, showing significant symptom improvement, with three maintaining their improvement at follow-up. Two patients dropped out due to time constraints and severe symptoms. No significant cultural differences were found in PD measures or AS subscales.

Conclusions:

ICBT seems effective for Arabic-speaking patients with mild to moderate PD, supporting wider implementation without major cultural adaptations. Qualitative feedback highlighted cultural considerations including communication preferences, family involvement, and need for culturally relevant examples. Specific cultural adaptations could enhance engagement while maintaining treatment effectiveness. Larger, more diverse samples are needed in future research. Clinical Trial: Not applicable


 Citation

Please cite as:

Halaj A, Kaiyal L, Andersson G, Andersson G, Huppert JD

Internet-Based Cognitive Behavioral Therapy for Panic Disorder Among Arabic-Speaking Patients: Case Series

JMIR Form Res 2026;10:e83415

DOI: 10.2196/83415

PMID: 43019539

Download PDF


Request queued. Please wait while the file is being generated. It may take some time.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.