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Kurtti A, Iivanainen S, Kaarteenaho R, Andersen H, Jekunen A, Vasankari T, Koivunen J
Effect of Lung Cancer Screening, Smoking Cessation, and Cessation Smartphone App to Health-Related Quality of Life Among Heavy Smokers: Randomized Controlled Trial
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
Effect of Lung Cancer Screening, Smoking Cessation, and Cessation Smartphone Application to Health-Related Quality-of-Life: a randomized controlled trial
Antti Kurtti;
Sanna Iivanainen;
Riitta Kaarteenaho;
Heidi Andersen;
Antti Jekunen;
Tuula Vasankari;
Jussi Koivunen
ABSTRACT
Background:
Smoking cessation intervention is recommended within the screening program for lung cancer. We have previously shown that Suunta smartphone application can increase the chance for smoking cessation along with lung cancer screening. Effects of lung cancer screening, smoking cessation, and use of smartphone application to health-related quality of life (HRQoL) are widely unknown.
Objective:
This study aims to investigate the effect of lung cancer screening, and use of smoking cessation application to HRQoL.
Methods:
LDCT-SC-FI (NCT05630950) is a 1:1 randomized controlled study (n=200) which investigated Suunta smoking cessation application in individuals undergoing low-dose CT (LDCT) screening for lung cancer. HRQoL, an exploratory study endpoint, was assessed at baseline and at one year with QLQ-C30 and EQ-5D.
Results:
199 and 186 individuals had both questionnaires completed at baseline and at one year, respectively. We did not detect a change in HRQoL between the time points using QLQ-C30 global health score (GHS) or EQ-5D index score. Smoking cessation at one year time did not affect QLQ-C30 GHS or EQ-5D. We observed improved quality of life mean scores by QLQ-C30 (68.46 vs. 74.82, p=0.027) and EQ-5D (0.720 vs. 0.799) in the application arm at one year while there was no difference at baseline. Smartphone application arm reported reduced pain, decreased fatigue, and increased mobility. The number of completed questionnaires in the application was associated with improved HRQoL.
Conclusions:
LDCT screening for lung cancer or smoking cessation was not associated with changes in HRQoL. Smoking cessation smartphone application use was associated with improved HRQoL mainly by decreased pain and fatigue. The results suggested that the benefits of Suunta smartphone application extend beyond smoking cessation. Clinical Trial: NCT05630950
Citation
Please cite as:
Kurtti A, Iivanainen S, Kaarteenaho R, Andersen H, Jekunen A, Vasankari T, Koivunen J
Effect of Lung Cancer Screening, Smoking Cessation, and Cessation Smartphone App to Health-Related Quality of Life Among Heavy Smokers: Randomized Controlled Trial
