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Accepted for/Published in: JMIR Cancer

Date Submitted: Jul 26, 2025
Date Accepted: Dec 22, 2025

The final, peer-reviewed published version of this preprint can be found here:

Patients’ Attitudes and Beliefs Toward Artificial Intelligence Use in Cancer Care: Cross-Sectional Survey Study

Santos Teles M, Bryl K, Chimonas S, Khan A, Epstein AS, Daly B, Xiao H, Mao JJ

Patients’ Attitudes and Beliefs Toward Artificial Intelligence Use in Cancer Care: Cross-Sectional Survey Study

JMIR Cancer 2026;12:e81346

DOI: 10.2196/81346

PMID: 41637748

PMCID: 12872120

Patients’ Attitudes and Beliefs Toward Artificial Intelligence Use in Cancer Care: A Cross-sectional Survey Study

  • Marco Santos Teles; 
  • Karolina Bryl; 
  • Susan Chimonas; 
  • Atif Khan; 
  • Andrew S Epstein; 
  • Bobby Daly; 
  • Han Xiao; 
  • Jun J Mao

ABSTRACT

Background:

Artificial Intelligence (AI) is being rapidly integrated into oncologic care, yet little is known about how patients perceive these applications. Understanding patient perceptions is critical to ensuring AI applications align with their needs and preferences.

Objective:

This study aimed to evaluate oncology patients’ attitudes and beliefs on the use of AI across clinical touchpoints in cancer care.

Methods:

We conducted a cross-sectional survey study with adult oncology patients from September to December 2024. The survey assessed patients’ comfort with AI use across 8 clinical touchpoints of cancer care (e.g. screening, diagnosis, treatment) on a 5-point Likert scale (1=very uncomfortable to 5=very comfortable). Patients also rated their concerns about AI, including potential harms related to its use (e.g. medical errors, privacy breaches), on a 3-point Likert scale (1=not concerned to 3= very concerned).

Results:

Of 383 patients approached, 330 (86.2% response rate) participated; 184 (55.9%) were male, 162 (49.4%) age 65 or older, 35 (10.8%) Black, 40 (12.1%) Hispanic or Latino, and 233 (72.6%) were actively receiving cancer treatment. Patients were most comfortable with AI use in cancer screening (80.2%), and supportive care applications, including exercise (78.2%), diet (74.8%), and herbs/supplements (72.4%). Patients were least comfortable with AI use to assist with diagnosis (70.4%), symptom management (67.5%), treatment planning (64.8%), and prognosis (61.5%). Nonetheless, about half (49.7%) were at least somewhat concerned with the use of AI in cancer care, most commonly loss of human interaction and medical errors.

Conclusions:

While the majority of oncology patients had a favorable view of AI in cancer care, nearly half had concerns about potential harms. Incorporating patient perspectives into AI development is essential for patient-centered and high-quality cancer care.


 Citation

Please cite as:

Santos Teles M, Bryl K, Chimonas S, Khan A, Epstein AS, Daly B, Xiao H, Mao JJ

Patients’ Attitudes and Beliefs Toward Artificial Intelligence Use in Cancer Care: Cross-Sectional Survey Study

JMIR Cancer 2026;12:e81346

DOI: 10.2196/81346

PMID: 41637748

PMCID: 12872120

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