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Accepted for/Published in: JMIR Human Factors

Date Submitted: Jul 26, 2025
Open Peer Review Period: Jul 26, 2025 - Sep 20, 2025
Date Accepted: Jan 22, 2026
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

AI-Enhanced Conversational Agents for Personalized Asthma Support in People With Asthma: Factors for Engagement, Value, and Efficacy in a Cross-Sectional Survey Study

Moradbakhti L, Peters D, Quint JK, Schuller B, Cook D, Calvo RA

AI-Enhanced Conversational Agents for Personalized Asthma Support in People With Asthma: Factors for Engagement, Value, and Efficacy in a Cross-Sectional Survey Study

JMIR Hum Factors 2026;13:e80979

DOI: 10.2196/80979

PMID: 41812152

AI-enhanced conversational agents for personalized asthma support: Factors for engagement, value and efficacy

  • Laura Moradbakhti; 
  • Dorian Peters; 
  • Jennifer K. Quint; 
  • Björn Schuller; 
  • Darren Cook; 
  • Rafael A. Calvo

ABSTRACT

Background:

Asthma-related deaths in the UK are the highest in Europe, and only 30% of patients access basic care. There is a need for alternative approaches to reaching people with asthma in order to provide health education, self-management support and bridges to care.

Objective:

Automated conversational agents (specifically, mobile chatbots) present opportunities for providing alternative and individually tailored access to health education, self-management support and risk self-assessment. But would patients engage with a chatbot, and what factors influence engagement?

Methods:

We present results from a patient survey (N=1257) devised by a team of asthma clinicians, patients, and technology developers, conducted to identify optimal factors for efficacy, value and engagement for a chatbot.

Results:

Results indicate that most adults with asthma (53%) are interested in using a chatbot and the patients most likely to do so are those who believe their asthma is more serious and who are less confident about self-management. Results also indicate enthusiasm for 24/7 access, personalisation, and for WhatsApp as the preferred access method (compared to app, voice assistant, SMS or website).

Conclusions:

Obstacles to uptake include security/privacy concerns and skepticism of technological capabilities. We present detailed findings and consolidate these into 7 recommendations for developers for optimising efficacy of chatbot-based health support.


 Citation

Please cite as:

Moradbakhti L, Peters D, Quint JK, Schuller B, Cook D, Calvo RA

AI-Enhanced Conversational Agents for Personalized Asthma Support in People With Asthma: Factors for Engagement, Value, and Efficacy in a Cross-Sectional Survey Study

JMIR Hum Factors 2026;13:e80979

DOI: 10.2196/80979

PMID: 41812152

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