Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: JMIR Aging

Date Submitted: Jul 9, 2025
Open Peer Review Period: Jul 9, 2025 - Sep 3, 2025
Date Accepted: Apr 9, 2026
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Effects of Multisensory Integration Training on Postural Stability Characteristics and Fall Risk in Older Adults: Systematic Review and Meta-Analysis

Guo C, Yin L, Chen P, Zhan J, Yu Z, Tan Teck C, Wei Y, Gong Y, Xu M, Van Minh L, Wang L

Effects of Multisensory Integration Training on Postural Stability Characteristics and Fall Risk in Older Adults: Systematic Review and Meta-Analysis

JMIR Aging 2026;9:e80345

DOI: 10.2196/80345

PMID: 42096607

Effects of Multisensory Integration Training on Postural Stability Characteristics and Fall Risk in Older Adults: A Systematic Review and Meta-Analysis

  • Chaoyu Guo; 
  • Lulu Yin; 
  • Peng Chen; 
  • Jianglong Zhan; 
  • Zhongqi Yu; 
  • Cheng Tan Teck; 
  • Yaru Wei; 
  • Yixue Gong; 
  • Menghan Xu; 
  • Le Van Minh; 
  • Lin Wang

ABSTRACT

Background:

Older adults' fall risk rises with age, linked to multi-system decline, sensory processing changes and postural control deficits. Multisensory integration (MSI) training enhances the brain's multisensory processing, but existing studies lack comparability due to varied intervention duration and type. Thus, this study intends to quantify MSI training's effects on older adults' postural stability and fall risk via systematic review and meta-analysis, and identify heterogeneity sources.

Objective:

This study aimed to systematically evaluate the effectiveness of multisensory integration (MSI) training on postural stability and fall risk in healthy older adults and provide an evidence-based basis for clinical practice.

Methods:

Databases including PubMed, Embase, and Cochrane Library were searched per PRISMA guidelines. Meta-analyses using R packages quantified effects via standardized mean differences (SMD) and 95% confidence intervals (CI), with fixed/random effects models selected based on heterogeneity (I²). Subgroup analyses explored age, intervention duration, and type.

Results:

Fifteen randomized controlled trials were included in the meta-analysis. Results showed that MSI training significantly reduced center of pressure displacement in the anterior–posterior displacement (SMD = 2.66, 95% CI [1.13, 4.20]) and center of pressure displacement in the medio–lateral displacement (SMD = 2.70, 95% CI [0.50, 4.90]). In terms of postural stability, MSI training significantly improved Berg balance scale scores (SMD = −3.42, 95% CI [−4.44, −2.41]), and Sensory Organization Test scores were significantly affected by age (SMD = −6.60, 95% CI [−13.06, −0.13]). 13.06, -0.13], P<0.001). In terms of fall risk, MSI training significantly improved Falls Efficacy Scale scores (SMD = 4.13, 95% CI [2.35, 5.91]); Timed up and go test completion time was significantly affected by intervention type (SMD = 1.14, 95% CI [0.46, 1.82], P < 0.001). Activity-specific balance confidence core was significantly affected by intervention time (SMD = −3.32, 95% CI [−8.80, 2.16], P = 0.03).

Conclusions:

MSI training can significantly improve static and dynamic postural control and reduce fear of falling scores, which implies that MSI training can improve postural stability and fall risk of older adults. Clinical Trial: CRD420251023158


 Citation

Please cite as:

Guo C, Yin L, Chen P, Zhan J, Yu Z, Tan Teck C, Wei Y, Gong Y, Xu M, Van Minh L, Wang L

Effects of Multisensory Integration Training on Postural Stability Characteristics and Fall Risk in Older Adults: Systematic Review and Meta-Analysis

JMIR Aging 2026;9:e80345

DOI: 10.2196/80345

PMID: 42096607

Download PDF


Request queued. Please wait while the file is being generated. It may take some time.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.