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Accepted for/Published in: JMIR Research Protocols

Date Submitted: Jul 1, 2025
Date Accepted: Nov 18, 2025

The final, peer-reviewed published version of this preprint can be found here:

Using AI Algorithms and Machine Learning in the Analysis of a Bio-Purification Method (Therapeutic Emesis, Known as “Vamana Karma”): Protocol for a Mixed Methods Study

kalra S, Rani P, Chauhan N, Gupta AR, Singh S, David R, PV A

Using AI Algorithms and Machine Learning in the Analysis of a Bio-Purification Method (Therapeutic Emesis, Known as “Vamana Karma”): Protocol for a Mixed Methods Study

JMIR Res Protoc 2026;15:e79875

DOI: 10.2196/79875

PMID: 41632954

PMCID: 12867470

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Establishing a Framework for Using AI Algorithms and Machine Learning in the Analysis of a Bio-Purification Method: Vamana (Therapeutic Emesis) in Traditional Systems of Medicine

  • Sumit kalra; 
  • Pooja Rani; 
  • Neha Chauhan; 
  • Ashutosh Ravi Gupta; 
  • Sachin Singh; 
  • Richard David; 
  • Anandaraman PV

ABSTRACT

Background:

Vamana Karma (therapeutic emesis) is a classical purification therapy in Ayurveda, particularly indicated for Kapha dominant conditions. In traditional diagnostics, there is predominant subjectivity in the visual assessment of the character and content of vomitus leading to observer bias and interobserver variability. The integration of artificial intelligence (AI) and machine learning (ML) has facilitated the elimination of subjectivity and the preservation of consistency in evaluating treatment responses.

Objective:

The study intends to make and test an AI-assisted digital framework for the study of Vamana Karma. With the framework, vomitus events will be identified, their content classified, and facial signs and reactions in the patient studied to strengthen the reliability and repeatability of the procedure’s review.

Methods:

A prospective observational study is being conducted at a tertiary Ayurveda institute. Video data of Vamana procedures are recorded using standardized protocols. A dataset of annotated images and videos is being developed for training YOLOv8-based object detection models and ResNet-based content classification models. DeepFace will be used for facial expression analysis. The system's performance will be evaluated using standard machine learning metrics, and agreement with expert assessments will be measured using Fleiss' Kappa statistic.

Results:

Participant enrollment and data collection are ongoing, with final results expected by July 2025. Preliminary data analysis and model training are in progress.

Conclusions:

The proposed AI framework has the potential to modernize and standardize the evaluation of Vamana Karma, reducing observer dependency and improving clinical reproducibility. Successful implementation could serve as a model for the integration of AI into traditional healthcare practices.


 Citation

Please cite as:

kalra S, Rani P, Chauhan N, Gupta AR, Singh S, David R, PV A

Using AI Algorithms and Machine Learning in the Analysis of a Bio-Purification Method (Therapeutic Emesis, Known as “Vamana Karma”): Protocol for a Mixed Methods Study

JMIR Res Protoc 2026;15:e79875

DOI: 10.2196/79875

PMID: 41632954

PMCID: 12867470

Per the author's request the PDF is not available.