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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Jun 25, 2025
Open Peer Review Period: Jun 25, 2025 - Aug 20, 2025
Date Accepted: Apr 27, 2026
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Effectiveness of a Home-Based and Group-Based Tele-Exercise Program for Breast Cancer Survivors: Pilot Randomized Controlled Trial

GAO Y, SUN Y, FUNG BKY, FUNG WWS, CHUN OK, XIONG Z, MAI L, WANG XY, Baker J

Effectiveness of a Home-Based and Group-Based Tele-Exercise Program for Breast Cancer Survivors: Pilot Randomized Controlled Trial

J Med Internet Res 2026;28:e79564

DOI: 10.2196/79564

PMID: 42361262

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Report on a pilot study of "a home-based and group-based tele-exercise program for breast cancer survivors: a randomized controlled trial"

  • Yang GAO; 
  • Yan SUN; 
  • Brigitte Kim Yook FUNG; 
  • Wai Wun Sara FUNG; 
  • Oi Kwan CHUN; 
  • Zhennan XIONG; 
  • Luyi MAI; 
  • Xue Ying WANG; 
  • Julian Baker

ABSTRACT

Background:

Breast cancer remains the most prevalent cancer among women globally, with significant incidence and mortality rates. Adjuvant therapies, while standard, often lead to adverse effects impacting physical and mental health. Exercise has shown potential in mitigating these effects, yet many breast cancer survivors remain insufficiently active.

Objective:

This study explores a novel 12-week tele-exercise protocol tailored for breast cancer survivors in Hong Kong, integrating psychological theories and behaviour change techniques to foster sustainable exercise habits.

Methods:

Conducted as a pilot study, this two-group randomized controlled trial involved 24 participants undergoing adjuvant therapy. The intervention group received a progressively supervised tele-exercise regimen, transitioning to unsupervised sessions, combined with psychological counselling. Outcomes were assessed using the RE-AIM framework, focusing on feasibility, acceptability, and preliminary health effects.

Results:

Results indicated high recruitment (70.6%) and retention (100%) rates, with satisfactory attendance (87.7%) and compliance (69.4%) in the intervention group. Participants reported high acceptability. Exercise-induced improvements in cardiopulmonary fitness (the primary outcome), lower extremity muscular strength, balance, shoulder ROM on the affected side, and health-related quality of life metrics were promising.

Conclusions:

This pilot demonstrates the acceptability, feasibility, and potential effectiveness of the tele-exercise in breast cancer rehabilitation, suggesting it as a viable alternative to traditional exercise interventions. Future research should explore long-term sustainability and broader applicability of tele-exercise to enhance recovery and quality of life among breast cancer survivors. Clinical Trial: NCT06382441


 Citation

Please cite as:

GAO Y, SUN Y, FUNG BKY, FUNG WWS, CHUN OK, XIONG Z, MAI L, WANG XY, Baker J

Effectiveness of a Home-Based and Group-Based Tele-Exercise Program for Breast Cancer Survivors: Pilot Randomized Controlled Trial

J Med Internet Res 2026;28:e79564

DOI: 10.2196/79564

PMID: 42361262

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