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Accepted for/Published in: JMIR Formative Research

Date Submitted: Jun 20, 2025
Open Peer Review Period: Jun 23, 2025 - Aug 18, 2025
Date Accepted: Sep 5, 2025
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

ChatGPT-Based Chatbot for Help Quitting Smoking via Text Messaging: An Interventional Study

Abroms L, Wysota C, Yousefi A, Wu TC, Broniatwoski D

ChatGPT-Based Chatbot for Help Quitting Smoking via Text Messaging: An Interventional Study

JMIR Form Res 2025;9:e79402

DOI: 10.2196/79402

PMID: 41072009

PMCID: 12552811

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Feasibility and Acceptability of a ChatGPT Chatbot for Help Quitting Smoking via Text Messaging

  • Lorien Abroms; 
  • Christina Wysota; 
  • Artin Yousefi; 
  • Tien-Chin Wu; 
  • David Broniatwoski

ABSTRACT

Background:

Large Language Model (LLM) chatbots such as ChatGPT may be able to provide support to people who smoke cigarettes and are trying to quit yet few studies have examined LLM chatbots.

Objective:

This pilot study examined the feasibility and acceptability of offering a specialized ChatGPT-based chatbot, BeFreeBot, integrated into a smoking cessation text-messaging program, BeFree.

Methods:

Participants who smoked cigarettes in the past 7 days were recruited from Amazon Mechanical Turk (N=23), enrolled in BeFree and provided access to BeFreeBot. Surveys were administered at baseline and again 4 weeks post-enrollment to assess perceptions of BeFreeBot. Computer records of interactions with BeFreeBot were also analyzed to assess participant engagement and BeFreeBot adherence to instructions.

Results:

Most participants (69.5%) texted BeFreeBot with questions or concerns at least once. Participants texted 14.5 (SD=23.6) texts to BeFreeBot on average. The majority of participants were highly satisfied with the BeFreeBot (72.2%) and agreed that it was helpful for quitting (57.9%). They also reported that the BeFreeBot responses were clear and easy to understand (94.1%), and that they trusted responses from the BeFreeBot (70.6%). The majority of participants (89.5%) reported trying to quit smoking for one day or longer, and 30.4% self-reported no smoking in the past 7 days. An analysis of transcripts of BeFreeBot responses (N=328) revealed that the BeFreeBot functioned as instructed on most measures, including on adherence to the US Preventive Services Task Force guidelines.

Conclusions:

A specialized LLM chatbot integrated into a text messaging program and accessed through text message was found to be feasible and acceptable to smokers.


 Citation

Please cite as:

Abroms L, Wysota C, Yousefi A, Wu TC, Broniatwoski D

ChatGPT-Based Chatbot for Help Quitting Smoking via Text Messaging: An Interventional Study

JMIR Form Res 2025;9:e79402

DOI: 10.2196/79402

PMID: 41072009

PMCID: 12552811

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