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Accepted for/Published in: JMIR Aging

Date Submitted: Jun 16, 2025
Date Accepted: Dec 18, 2025

The final, peer-reviewed published version of this preprint can be found here:

Predicting Adherence to Computer-Based Cognitive Training Programs Among Older Adults Using Source-Free Domain Adaptation: Algorithm Development and Validation

Subedi R, Chakraborty S, He Z, Pang Y, Zhang S, Lustria M, Charness N, Boot W

Predicting Adherence to Computer-Based Cognitive Training Programs Among Older Adults Using Source-Free Domain Adaptation: Algorithm Development and Validation

JMIR Aging 2026;9:e79123

DOI: 10.2196/79123

PMID: 41848218

Predicting Adherence to Computer-based Cognitive Training Programs Among Older Adults Using Source-free Domain Adaptation: Algorithm Development and Validation

  • Ronast Subedi; 
  • Shayok Chakraborty; 
  • Zhe He; 
  • Yuanying Pang; 
  • Shenghao Zhang; 
  • Mia Lustria; 
  • Neil Charness; 
  • Walter Boot

ABSTRACT

Background:

Cognitive decline in the aging population presents an unprecedented challenge worldwide. Recent research has shown the potential of cognitive training programs to mitigate cognitive decline. However, these interventions require sustained adherence to be effective, which can be challenging.

Objective:

In this study, we aim to enhance the accuracy of predicting adherence patterns in cognitive training programs for older adults, with the goal of developing personalized support systems that promote and improve cognitive outcomes.

Methods:

A major challenge in developing deep neural networks for predicting adherence patterns is the limited availability of individual participant’s training data. While Domain Adaptation (DA) techniques can address this issue by leveraging training data from other clinical studies, our research considers a more practical scenario where the use of data from other studies can be restricted due to privacy and confidentiality concerns. We used Source-Free Domain Adaptation (SFDA), which utilizes models trained on other cognitive studies, without requiring access to the corresponding datasets. To the best of our knowledge, this is the first effort to use SFDA to predict older adults’ daily adherence to cognitive training programs.

Results:

Our results on three previously conducted cognitive training intervention studies demonstrated the efficacy of deep learning and SFDA to accurately predict adherence lapses, while addressing data privacy concerns.

Conclusions:

Our findings indicate that deep learning and SFDA techniques can be useful in the development of adherence support systems for computerized cognitive training, aimed at improving the health and well-being of older adults.


 Citation

Please cite as:

Subedi R, Chakraborty S, He Z, Pang Y, Zhang S, Lustria M, Charness N, Boot W

Predicting Adherence to Computer-Based Cognitive Training Programs Among Older Adults Using Source-Free Domain Adaptation: Algorithm Development and Validation

JMIR Aging 2026;9:e79123

DOI: 10.2196/79123

PMID: 41848218

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