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Currently submitted to: Journal of Medical Internet Research

Date Submitted: Jun 15, 2025

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Artificial Intelligence and New Healthcare Technologies: A Global Perspective

  • Abubakr Ziuallah; 
  • Jonathan A Tangsrivimol; 
  • Erfan Darzidehkalani; 
  • Hafeez Ul Hassan Virk; 
  • Wang Zhen; 
  • Jan Egger; 
  • Sean Hacking; 
  • Iqra Riaz; 
  • Angus Turner; 
  • De-Kuang Hwang; 
  • Elena Giovanna Bignami; 
  • Yusuf Qadeer; 
  • Joshua Au Yeung; 
  • Benjamin S Glicksberg; 
  • Hugo J W L Aerts; 
  • Markus Strauss; 
  • Chayakrit Krittanawong

ABSTRACT

Background:

The convergence of telemedicine and artificial intelligence (AI) represents a transformative force in healthcare delivery with potential to both reduce and exacerbate disparities. Despite accelerated adoption during the COVID-19 pandemic, a comprehensive assessment of AI-enhanced telemedicine across healthcare dimensions remains incomplete.

Objective:

To examine the intersection of AI and telemedicine at patient, organizational, and population levels, highlighting opportunities, challenges, and emerging applications while identifying strategies to ensure equitable implementation.

Methods:

This narrative review synthesizes evidence from peer-reviewed literature, clinical trials, and commercial applications to evaluate AI-telemedicine integration. We analyze diagnostic applications, monitoring technologies, and decision support systems at the individual patient level; operational implementations and workflow optimizations at the organizational level; and predictive modeling, resource allocation, and public health surveillance at the population level.

Results:

AI applications in telemedicine demonstrate substantial promise, with diagnostic algorithms approaching or exceeding expert-level performance in specialties including dermatology (AUC >0.90), ophthalmology (sensitivity >90%), and cardiology. Organizations implementing AI-enhanced telehealth report improved operational efficiency and resource utilization. Population-level applications show particular utility in disease surveillance, pandemic response, and addressing healthcare disparities, though significant challenges remain in algorithm bias, data privacy, and equitable access. The emerging landscape of foundation models offers improved generalizability across diverse populations but requires rigorous validation to prevent amplification of existing inequities.

Conclusions:

AI-enhanced telemedicine can potentially transform healthcare delivery by increasing access to specialized expertise, optimizing resource allocation, and enabling personalized care. However, realizing these benefits requires addressing interoperability challenges, mitigating algorithmic bias, ensuring data privacy, and developing regulatory frameworks that balance innovation with patient safety. Future research should focus on prospective validation of AI applications in diverse populations and care settings to ensure equitable implementation.


 Citation

Please cite as:

Ziuallah A, Tangsrivimol JA, Darzidehkalani E, Ul Hassan Virk H, Zhen W, Egger J, Hacking S, Riaz I, Turner A, Hwang DK, Bignami EG, Qadeer Y, Yeung JA, Glicksberg BS, Aerts HJWL, Strauss M, Krittanawong C

Artificial Intelligence and New Healthcare Technologies: A Global Perspective

JMIR Preprints. 15/06/2025:79103

DOI: 10.2196/preprints.79103

URL: https://preprints.jmir.org/preprint/79103

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