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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Jun 12, 2025
Date Accepted: Feb 13, 2026

The final, peer-reviewed published version of this preprint can be found here:

Technology-Based Interventions for Prevention of Type 2 Diabetes Following Gestational Diabetes: Systematic Review and Meta-Analysis

Eades C, Nguyen-Hoang A, Hoyle L, Cameron D, Evans JM

Technology-Based Interventions for Prevention of Type 2 Diabetes Following Gestational Diabetes: Systematic Review and Meta-Analysis

J Med Internet Res 2026;28:e78841

DOI: 10.2196/78841

PMID: 41921207

Technology based interventions for prevention of type 2 diabetes following gestational diabetes: A systematic review and meta-analysis

  • Claire Eades; 
  • Anh Nguyen-Hoang; 
  • Louise Hoyle; 
  • Dawn Cameron; 
  • Josie MM Evans

ABSTRACT

Background:

Women who have had gestational diabetes are at an eight-fold increased risk of developing type 2 diabetes, but positive lifestyle change can prevent or delay progression to type 2 diabetes. Technology based interventions offer a solution to help to overcome the challenges that women face in making postpartum lifestyle changes.

Objective:

To assess whether technology-based diabetes prevention interventions are effective in improving outcomes related to the onset of type 2 diabetes among women with a previous diagnosis of gestational diabetes.

Methods:

The protocol was registered with the international prospective register of systematic reviews (PROSPERO; CRD42024324019). MEDLINE, CENTRAL, CINAHL, EMBASE, PsycINFO and MIDRIS were searched up to October 2025 using a combination of database subject headings and free text. Titles and abstracts of all articles were independently screened by two authors, as were full text articles that were retrieved. Experimental or non-experimental studies were eligible if they examined the use of a technology-based diabetes prevention intervention for women delivered between gestational diabetes diagnosis and any time in the postpartum period, and assessed either anthropometric outcomes, glycaemic control, health behaviour or psychological outcomes. Risk of bias was assessed by one reviewer using National Institute for Clinical Excellence checklist. Data were summarised narratively, and results were pooled, where possible, using a random effects model analysing the between group differences in each outcome

Results:

This systematic review identified 15 studies reported in 17 papers including a total of 1,257 participants. Two out of 12 studies assessing weight and one out of five studies assessing glycaemic control reported significant differences favouring the intervention. One study assessed type 2 diabetes prevalence and found no significant differences between the intervention and control group. Pooled analysis of seven studies revealed a significantly greater weight loss among those receiving technology-based interventions with a mean difference of -1.01kg (-1.86 to -0.16). Interventions delivered using technology and with a longer follow up resulted in increased weight loss (mean difference –1.13 & -1.58kg respectively) compared to those using combined technology and telemedicine approaches (mean difference –0.89kg) and studies with a shorter follow up (mean difference –0.7kg) but the difference was not significant. Meta-analysis showed no significant differences in fasting glucose, two-hour glucose, HbA1c or HOMA-IR.

Conclusions:

Limitations of the evidence in the review were the small sample sizes, lack of power calculations and poorly described interventions lacking theoretical basis. This review is the first to summarise interventions with primarily technology-based delivery in this population and to code the BCTs. The findings suggest that that there may be potential for technology-based interventions to support women in reducing their risk of type 2 diabetes following GDM but trials with larger samples and longer follow up are required to allow firm conclusions to be drawn.


 Citation

Please cite as:

Eades C, Nguyen-Hoang A, Hoyle L, Cameron D, Evans JM

Technology-Based Interventions for Prevention of Type 2 Diabetes Following Gestational Diabetes: Systematic Review and Meta-Analysis

J Med Internet Res 2026;28:e78841

DOI: 10.2196/78841

PMID: 41921207

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