Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: JMIR Research Protocols

Date Submitted: Jun 11, 2025
Open Peer Review Period: Jun 11, 2025 - Aug 6, 2025
Date Accepted: Nov 27, 2025
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Effectiveness and Cost-Effectiveness of a Digital Falls Prevention Program Versus Usual Care to Improve Balance, Falls Risk, and Function in Older Adults: Protocol for the Keep-On-Keep-Up Randomized Controlled Trial

Stanmore E, Parchment A, Odebiyi B, Bower P, French C, Shi C, Ahmed S, Dowding D, Dumville J, Kislov R, Thompson A, Skelton DA, Clarke M, Todd C

Effectiveness and Cost-Effectiveness of a Digital Falls Prevention Program Versus Usual Care to Improve Balance, Falls Risk, and Function in Older Adults: Protocol for the Keep-On-Keep-Up Randomized Controlled Trial

JMIR Res Protoc 2026;15:e78840

DOI: 10.2196/78840

PMID: 41643062

PMCID: 12875423

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Effectiveness and cost-effectiveness of a digital falls' prevention programme versus usual care to improve balance, falls risk and function in older adults: protocol for the KOKU randomised controlled trial

  • Emma Stanmore; 
  • Amelia Parchment; 
  • Bolanle Odebiyi; 
  • Peter Bower; 
  • Chloe French; 
  • Chunhu Shi; 
  • Saima Ahmed; 
  • Dawn Dowding; 
  • Jo Dumville; 
  • Roman Kislov; 
  • Alex Thompson; 
  • Dawn A Skelton; 
  • Margaret Clarke; 
  • Chris Todd

ABSTRACT

Background:

Falls are the primary cause of fatal and non-fatal accidental injuries in older adults. The World Falls Prevention Guidelines recommend balance-challenging, functional exercise programmes as a key strategy for falls prevention but access, uptake and adherence to these programmes in community settings remain suboptimal. Keep-On-Keep-Up (KOKU), a digital, National Health Service (NHS) approved programme was co-developed with older adults and therapists, to provide progressive, evidence-based exercises and to raise awareness of fall prevention strategies.

Objective:

This trial aims to investigate the effectiveness and cost-effectiveness of the KOKU digital strength and balance programme for improving balance, enhancing physical function and reducing falls risk among community dwelling older adults.

Methods:

This is a two-arm, parallel group randomised controlled trial. A total of 196 community dwelling older adults aged 60 years and older will be randomised to either the intervention group comprising a digital strength and balance programme (KOKU) alongside standard care (strength and balance exercise advice and a falls prevention leaflet) or to a control group, receiving standard care only. Participants receiving the intervention will be asked to exercise three times per week following the tailored and progressive programme. Randomisation will take place after recruitment and baseline data collection. The trial’s primary outcome measure is balance function (Berg Balance Score) at twelve weeks post-randomisation. Secondary trial outcomes include: lower limb strength; healthcare utilisation and health-related quality of life; self-reported concerns about falling; self-reported physical activity; falls risk, pain, mood, fatigue, self-reported falls, acceptability and usability of the KOKU programme. Intention to treat analysis and a cost-effectiveness analysis will be employed for trial data analysis. Qualitative interviews and focus groups will be undertaken with around 10 care providers and 13 participants to further understand views of the intervention and trial processes.

Results:

This study began recruitment in July 2024 and concluded in March 2024 recruiting a total of 202 participants (102 intervention and 100 control). Following protocol publication, data compilation and analysis will be conducted, with results anticipated to be published in 2027.

Conclusions:

This trial will provide important evidence on whether a digital strength and balance programme can improve balance and related outcomes in older adults compared to usual care. Clinical Trial: ClinicalTrials.gov: NCT06687135


 Citation

Please cite as:

Stanmore E, Parchment A, Odebiyi B, Bower P, French C, Shi C, Ahmed S, Dowding D, Dumville J, Kislov R, Thompson A, Skelton DA, Clarke M, Todd C

Effectiveness and Cost-Effectiveness of a Digital Falls Prevention Program Versus Usual Care to Improve Balance, Falls Risk, and Function in Older Adults: Protocol for the Keep-On-Keep-Up Randomized Controlled Trial

JMIR Res Protoc 2026;15:e78840

DOI: 10.2196/78840

PMID: 41643062

PMCID: 12875423

Download PDF


Request queued. Please wait while the file is being generated. It may take some time.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.