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Accepted for/Published in: Interactive Journal of Medical Research

Date Submitted: May 22, 2025
Date Accepted: Jan 2, 2026

The final, peer-reviewed published version of this preprint can be found here:

An Eye-Opening Approach: Cancer of Unknown Primary Source With Choroidal Metastasis Case Report

Kaser E, Blaschke A, Barve V, Fry C, Waldman CW, Hackman S, William K

An Eye-Opening Approach: Cancer of Unknown Primary Source With Choroidal Metastasis Case Report

Interact J Med Res 2026;15:e77895

DOI: 10.2196/77895

PMID: 41643211

PMCID: 12875659

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

An Eye Opening Approach: Non-Small Cell Lung Cancer with Choroidal Metastasis Case Report

  • Erin Kaser; 
  • Alexander Blaschke; 
  • Vedin Barve; 
  • Constance Fry; 
  • Corey W. Waldman; 
  • Sarah Hackman; 
  • Kelly William

ABSTRACT

Choroid metastases represent a unique clinical challenge, threatening vision and overall prognosis. This case examines a 34-year-old male presenting with acute onset unilateral vision loss ultimately determined to be choroidal metastasis from non-small cell lung carcinoma. His treatment regimen involved an aggressive oligometastatic approach incorporating chemotherapy, immune checkpoint blockade, anti-angiogenics, and stereotactic radiosurgery with robust and durable response.


 Citation

Please cite as:

Kaser E, Blaschke A, Barve V, Fry C, Waldman CW, Hackman S, William K

An Eye-Opening Approach: Cancer of Unknown Primary Source With Choroidal Metastasis Case Report

Interact J Med Res 2026;15:e77895

DOI: 10.2196/77895

PMID: 41643211

PMCID: 12875659

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